Results 21 to 30 of about 37,478 (219)

Periodontal disease and risk of benign prostate hyperplasia: a cross-sectional study

open access: yesMilitary Medical Research, 2019
Background Both periodontal disease and benign prostatic hyperplasia are age-related diseases that affect millions of people worldwide. Hence, this study aimed to investigate the association between periodontal disease and the risk of benign prostatic ...
Lan Wu   +8 more
doaj   +1 more source

Expert consensus on Rezūm™: Indications, surgical technique and postoperative care

open access: yesBJUI Compass
Background Lower urinary tract symptoms associated to benign prostatic hyperplasia (LUTS/BPH) is a growing condition in males associated to a high clinical, economic and humanistic burden.
Emilio López Alcina   +4 more
doaj   +1 more source

Immunohistochemical Expression of Nkx3.1 in Prostatic Adenocarcinoma and Benign Prostatic Hyperplasia at a Tertiary Care Hospital in Karachi

open access: yesJournal of Gandhara Medical and Dental Sciences, 2023
OBJECTIVES To determine NKX3.1 expression in prostatic adenocarcinoma and benign prostate hyperplasia on Immunohistochemistry at a tertiary care hospital in Karachi.
Beenish Hussain   +5 more
doaj   +1 more source

Single-Cell and Spatial Transcriptomics Uncover Immune Dynamics and Cellular Heterogeneity in Benign Prostatic Hyperplasia and Prostate Cancer Transition. [PDF]

open access: yesMedComm (2020)
Leveraging integrated single‐cell and spatial transcriptomics, we delineated the sustained immunosuppressive landscape during prostate disease progression. Based on this, we have developed a precise gene‐based diagnostic classifier and a multimodal prognostic model.
Luo Y   +18 more
europepmc   +2 more sources

Benign Prostatic Hyperplasia and Prostate Cancer [PDF]

open access: yesEpidemiologic Reviews, 2001
This paper reviews the epidemiologic studies of benign prostatic hyperplasia in relation to prostate cancer. Such relation was investigated in epidemiologic studies but none have provided clear evidence suggesting an etiologic role for benign prostatic hyperplasia in the development of prostatic cancer.
openaire   +2 more sources

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu   +20 more
wiley   +1 more source

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse   +3 more
wiley   +1 more source

Pathology of benign prostatic hyperplasia [PDF]

open access: yesInternational Journal of Impotence Research, 2008
The epidemiology of benign prostatic hyperplasia (BPH) is complex and not fully understood. The androgenic hormones testosterones and dihydrotestosterone play at least a permissive and important role. Growth factors and other hormones including estrogens may also play a role.
openaire   +2 more sources

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

open access: yesChemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

THE EFFECT OF FINASTERIDE ON BLEEDING DURING TRANSURETHRAL RESECTION OF THE PROSTATE

open access: yesThe Iraqi Journal of Medical Sciences, 2016
Background: Finasteride is a selective 5-? reductase enzyme inhibitor that blocks the conversion of testosterone to dihydrotestosterone, down regulates prostatic angiogenesis and blood flow and promotes apoptosis of prostatic cells.
Firas S. Al-Qurayshe   +2 more
doaj   +4 more sources

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