Results 121 to 130 of about 1,640,389 (263)

Proteomics identification of overexpressed serum proteins in dogs with Babesiacanis infection. [PDF]

Vet World, 2023
Ritchoo S, Havanapan PO, Sussadee M, Maneeruttanarungroj C, Rucksaken R.   +4 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Impact of single freeze-thaw cycles on human serum proteins: Implications for mass spectrometry biomarker validation. [PDF]

iScience
Sauer T, Oberländer M, Maushagen R, Radloff H, Braun R, Honselmann K, Wellner U, Habermann J, Benecke C, Keck T, Szymczak S, Gemoll T.   +11 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The Binding Affinities of Serum Proteins to Nanoparticles. [PDF]

J Am Chem Soc
Stordy BP, Sepahi Z, Patrón GD, Yang W, Goodson AD, Blackadar C, Tavares AJ, Lin G, Malekjahani A, Ling B, Ravichandran R, Hicks DR, Shapiro MG, Zhang M, King NP, Baker D, Ricardez-Sandoval LA, Chan WCW.   +17 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Prospective associations of obesity heterogeneity, serum proteins, and carotid atherosclerosis risk. [PDF]

EBioMedicine
Zhong H, Chen J, Jia S, Chen H, Xi Y, Yan Y, Lu Z, Xiao C, Xu F, Tang J, Zheng JS, Chen YM.   +11 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Changes in Serum Proteins in Firefighters Responding to the 2025 Los Angeles Urban Conflagrations. [PDF]

J Occup Environ Med
Furlong M, Beitel SC, Conner R, Goodrich JM, Ding X, Rahn M, Stricker K, Guggenheim A, Hamilton A, Biering D, Hughes J, Gulotta JJ, Porter C, Hollister J, Burgess JL.   +14 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source