Results 211 to 220 of about 1,006,166 (271)

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Editorial: Novel and promising laboratory biomarkers for allergic disease diagnosis and prognosis: clinical applicability

Frontiers in Allergy
Henry Velazquez-Soto, Xin Wang, Xin Wang, María C. Jiménez-Martínez, María C. Jiménez-Martínez   +4 more
doaj   +1 more source

Case Report: Glatiramer Acetate-Induced Serum Sickness. [PDF]

Int J MS Care, 2017
Ferguson P.
europepmc   +1 more source

Triglyceride Polygenic Score Identifies Individuals Who May Respond Differently to Aspirin in Primary Prevention

Clinical Pharmacology &Therapeutics, EarlyView.
Low‐dose aspirin is no longer routinely recommended for the primary prevention of cardiovascular disease in older adults due to a lack of net benefit over bleeding risk. We hypothesized that genetic subgroups may experience differential harm or benefit from aspirin therapy.
Peter D. Fransquet, Chenglong Yu, Cammie Tran, Sultana Monira Hussain, Chad A. Bousman, Mark R. Nelson, Andrew M. Tonkin, John J. McNeil, Paul Lacaze   +8 more
wiley   +1 more source

A rapid desensitization protocol in a case of drotaverine-induced serum sickness-like reaction in a pregnant woman: A case report. [PDF]

Exp Ther Med, 2019
Ali S, Corcea SL, Cristian RM, Bumbacea RS.   +3 more
europepmc   +1 more source

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

Drug Testing and Analysis, EarlyView.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum, Shao‐Hsin Hung, Meng‐Tsang Hsieh, Mei‐Chich Hsu, William Chih‐Wei Chang   +4 more
wiley   +1 more source

Cortical Thickness and Appetite Hormones in Adolescent Obesity and Binge Eating Disorder: A Comparative Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study examined cortical thickness and appetite‐regulating hormones—neuropeptide Y (NPY) and ghrelin—to better understand the neurobiological mechanisms underlying binge eating disorder (BED) and obesity in adolescence. We compared adolescents with BED and obesity, adolescents with obesity without BED, and healthy controls (HCs),
Serkan Turan, İbrahim Mert Erbaş, Fatma Ceren Sarıoğlu, Berrin Çavuşoğlu, Ezgi Molla, Ali Rıza Şişman, Sevay Alsen Güney, Handan Güleryüz, Ayhan Abacı, Yeşim Öztürk, Aynur Pekcanlar Akay   +10 more
wiley   +1 more source

Serum sickness with refractory nephrotic syndrome following treatment with rituximab. [PDF]

CEN Case Rep, 2018
Maeda R, Kawasaki Y, Ohara S, Suyama K, Hosoya M.   +4 more
europepmc   +1 more source