Results 121 to 130 of about 1,892,741 (310)

AKURASI METODE PENGOLAHAN SERUM LIPEMIK TERHADAP PEMERIKSAAN KADAR PROTEIN TOTAL

, 2023
Latar belakang: Serum lipemik merupakan serum yang keruh berwarna putih susu yang disebabkan oleh akumulasi partikel lipoprotein yang berlebih dalam darah.
Rospitasari, Imbang
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Novel fluorescent probes for analysis of protein interactions under truly physiological conditions with real medical devices

, 2012
PhDProtein adsorption under physiological conditions was recognised to be the key step in the modulation of biological responses between materials and an osseous environment.
Mafina, Marc-Krystelle
core  

Dietary protein energy supplementation of pregnant Asian mothers at Sorrento, Birmingham. I: unselective during second and third trimesters

, 1982
At Sorrento Maternity Hospital Asian mothers whose babies had grown poorly in utero had anthropometric and biochemical evidence suggesting an inadequate nutritional state.
Wharton, P., Mansfield, H.N., P H Scott, O A Viegas, T J Cole, Scott, P.H., B A Wharton, Wharton, B.A., P Wharton, H N Mansfield, Viegas, O.A., Cole, T.J.   +11 more
core   +1 more source

Effect of Blood Sampling Time After Colostrum Intake on the Concentration of Metabolites Indicative of the Passive Immunity Transfer in Newborn Dairy Calves

Animals
Due to the synepitheliochorial placental structure, bovines show no maternal antibody flow from mother to fetus during pregnancy, resulting in an agammaglobulemic newborn [...]
Mohammad Hassan Mortazavi, Nathalia Brito Rocha, Marília Ribeiro de Paula, Evangelina Miqueo, Marcia Saladini Vieira Salles, Paulo Henrique Mazza Rodrigues, Carla Maris Machado Bittar   +6 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Relationship between serum calcium and CA 19-9 levels in colorectal cancer

, 2004
AIM: To examine the calcium metabolism of colorectal cancer (CRC) in patients with colorectal cancer and control patients. METHODS: Seventy newly diagnosed CRC patients were included.
Papp, János, Speer, Gábor, Lakatos, Péter László, Nagy, Zsolt, Fuszek, Péter, Tabák, Ádám, Horváth, Henrik Csaba, Lakatos, Péter, Takács, István   +8 more
core  

Functional activities of C-reactive protein on neutrophils [PDF]

C-reactive protein (CRP) is a member of the pentraxin family which opsonises S. pneumoniae through its binding to phosphorylcholine. In addition, CRP binds to Fcγ receptors: FcγRI with high affinity and, probably, FcγRIIA with lower affinity.
Rodriguez, Jairo Antonio
core   +1 more source