Results 171 to 180 of about 77,106 (306)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Título: Opera omnia

open access: yes
Sign.: [cristus], 2[cristus], à, A-Z, 2A-2MPort. con grav.
Gutiérrez, Juan
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Título: Practicarum quaestionum civilium ... liber tertius, quartus et quintus

open access: yes
Sign.: â\p4\s, A-R\p6\s, S\p4\s, A-N\p6\sPort. con grab. xilTexto a dos colPort. con grav.
Gutiérrez, Juan
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

D.D. Francisci Amostazo ... Alvearensis ... De causis piis in genere, et in specie libri VIII... : tomus primus

open access: yes
3 ej. de la misma obraTít. en antep.: "D.D. Francisci Amostazo De causis piis ; accedit Io. Baptistae Bassi Tractatus de sodalitiis, seu confraternitatibus ecclesiasticis et laicalibus, cum additione opusculi De vicario apostolico"Marca tip. en port.
Mostazo, Francisco, Servant, Antoine
core  

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