Results 91 to 100 of about 181,344 (276)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Examining the Effect of Servant Leadership on Organisational Trust and Organisational Citizenship Behaviour [PDF]

open access: yesInternational Journal of Management, Accounting and Economics
The aim of this study is to examine the effect of servant leadership on organisational trust and organisational citizenship behaviour. The population of the study consists of nurses who were employed in three private hospitals owned by a health group in ...
Huzeyfe Aydoğan, Özlem Özer
doaj   +1 more source

The Antecedents And Characteristics Of Academic Servant Leadership: A Case Study In A Faith-Based University In Indonesia [PDF]

open access: yes, 2016
This study explores the practice of academic servant leadership in a faith-based university in Indonesia. The exploration is intended to understand the origin of academic servant leadership and the characteristics of an academic servant leader.
Ricky, Ricky
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The Effect of Servant Leadership and Loyalty on Employee Performance at Khairu Ummah Syariah Service Cooperative

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study aims to examine the influence of servant leadership on employee performance, with employee loyalty as a mediating variable, at Koperasi Jasa Syariah Khairu Ummah.
Imam Akbari   +2 more
doaj   +1 more source

Can Servant Leaders Fuel the Leadership Fire? The Relationship between Servant Leadership and Followers’ Leadership Avoidance

open access: yesAdministrative Sciences, 2017
This study tested the effect of servant leadership on followers’ inclinations to strive for and, in contrast, to avoid leadership responsibility. Results from a study in the health care context, including two waves of data from 222 employees, revealed ...
Martin Lacroix, Armin Pircher Verdorfer
doaj   +1 more source

Understanding Face and Shame: A Servant-Leadership and Face Management Model

open access: yes, 2019
Clergy can have a negative impact on churches and other individuals when they knowingly or unknowingly attempt to save face, that is, try to protect their standing or reputation.
Bailey K. E.   +53 more
core   +1 more source

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