Results 121 to 130 of about 1,516,815 (340)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

İlk müstakil gazetenin tarihini açan Agâh Efendi ve gazetesi "Tercümanı Ahval" [PDF]

open access: yes
Taha Toros Arşivi, Dosya No: 49-Agah EfendiUnutma İstanbul projesi İstanbul Kalkınma Ajansı'nın 2016 yılı "Yenilikçi ve Yaratıcı İstanbul Mali Destek Programı" kapsamında desteklenmiştir.
İskit, Server
core  

A New Approach for Handling Null Values in Web Server Log [PDF]

open access: hybrid, 2010
Pradeep Ahirwar   +2 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

IMPLEMENTASI INDEX MYSQL DAN SERVER-SIDE DATATABLES UNTUK OPTIMALISASI PEMROSESAN DATA SISTEM MBKM FIK BERBASIS CODEIGNITER 4

open access: yesDinamika Rekayasa
Penelitian ini dilatar belakangi untuk mengatasi permasalahan yang dihadapi oleh Sistem Merdeka Belajar-Kampus Merdeka (MBKM) di Fakultas Ilmu Komputer Universitas Dian Nuswantoro (FIK UDINUS).
Renjiro Azhar Pramono   +2 more
doaj   +1 more source

Open data and data sharing in articles about COVID-19 published in preprint servers medRxiv and bioRxiv [PDF]

open access: bronze, 2022
Josip Strčić   +5 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Research and Experiment on Energy-Conservation Cooling Technique in IDC

open access: yesDianxin kexue, 2014
Beginning with Fourier Law and dealing with centralized and dispersive heat source in server with their merits, the architecture named parallel double-channels was proposed, which consist of “contact-type”and“non-contact-type”channels with significant ...
Yongshuang, Qiu Wenbo Lin   +1 more
doaj  

Latency Optimal Storage and Scheduling of Replicated Fragments for Memory Constrained Servers [PDF]

open access: green, 2022
Rooji Jinan   +3 more
openalex   +1 more source

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