Results 101 to 110 of about 1,481,271 (291)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

LBS avanzati su dispositivi PDA II° parte

open access: yesGEOmedia, 2014
LBS avanzati su dispositivi PDA II ...
Francesco Bartoli, Fabrizio Bernardini
doaj   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

GPS e Internet per fare la "differenza"

open access: yesGEOmedia, 2016
GPS ed Internet per fare la "differenza"
Fabrizio Bernardini
doaj   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Server transition process to AWS servers

open access: yes, 2012
Our aging server which has run for 5+ years the OBF sites has finally reached end of its lifespan. We are currently migrating sites to AWS volumes and sites for a temporary period while we decide about how to continue to support these services in the future.
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Considering Interactions among Multiple Criteria for the Server Selection

open access: yesJournal of Information and Organizational Sciences, 2010
Decision-making about server selection is one of the multi-criteria decision-making (MCDM) processes where interactions among criteria should be considered.
Vesna Čančer
doaj  

MACRO SYNTHESIS OF WIDE AREA COMPUTER NETWORKS AT NONLINEAR COSTS

open access: yesJournal of Engineering Science (Chişinău)
In practice, simple solutions of quick preliminary estimation of basic characteristics of a wide area computer network sometimes are needed. To achieve this goal, the backbone data transfer subnet and server set of computer networks are opportune to ...
BOLUN, Ion
doaj   +1 more source

The Possibilities of WWW Utilization for Process Control [PDF]

open access: yesActa Montanistica Slovaca, 1999
The contribution deals with the possibilities of www technology utilization in real time process control and describes the representation of this information on client site in the www page form.
Roškanin Martin, Horovčák Pavel
doaj  

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