Results 131 to 140 of about 1,516,815 (340)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Improving SQL Server Perform [PDF]

open access: yes
With the development of client server technology and multilayer architectures the systems ef-ficiency issue has been increasingly discussed. Lacking knowledge in optimization methods and tools offered by DBMS's, database administrators and developers of ...
Nicolae MERCIOIU, Victor VLADUCU
core  

MCP-Bench: Benchmarking Tool-Using LLM Agents with Complex Real-World Tasks via MCP Servers [PDF]

open access: green
Zhenting Wang   +10 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Reliability analysis of clustered systems with high availability directly attached storage devices

open access: yesDoklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki, 2019
The article describes an approach to reliability analysis of clustered systems with a direct connection one and two storage devices, and server systems in the case when the query time extremely limited.
A. L. Panin   +3 more
doaj  

Obsea servers network

open access: yesInstrumentation viewpoint, 2009
Peer ...
Cadena Muñoz, Francisco Javier   +4 more
openaire   +3 more sources

Server-Side Local Gradient Averaging and Learning Rate Acceleration for Scalable Split Learning [PDF]

open access: green, 2021
Shraman Pal   +7 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

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