Results 141 to 150 of about 1,718,808 (353)

BAGEL4: a user-friendly web server to thoroughly mine RiPPs and bacteriocins

Nucleic Acids Res., 2018
Interest in secondary metabolites such as RiPPs (ribosomally synthesized and posttranslationally modified peptides) is increasing worldwide. To facilitate the research in this field we have updated our mining web server.
A. J. Heel, A. Jong, Chunxu Song, Jakob H. Viel, J. Kok, O. Kuipers   +5 more
semanticscholar   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Considering Interactions among Multiple Criteria for the Server Selection

Journal of Information and Organizational Sciences, 2010
Decision-making about server selection is one of the multi-criteria decision-making (MCDM) processes where interactions among criteria should be considered.
Vesna Čančer
doaj  

psRNATarget: a plant small RNA target analysis server (2017 release)

Nucleic Acids Res., 2018
Plant regulatory small RNAs (sRNAs), which include most microRNAs (miRNAs) and a subset of small interfering RNAs (siRNAs), such as the phased siRNAs (phasiRNAs), play important roles in regulating gene expression.
X. Dai, Zhaohong Zhuang, P. Zhao
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Non-interactive fuzzy private matching [PDF]

, 2007
Two fuzzy private matching protocols are introduced to allow a client to securely compare a list of words to a server list, and discover only those words on the server list that are similar to his, while the server learns nothing.
Doumen, J.M.
core   +1 more source

A Large Closed Queueing Network Containing Two Types of Node and Multiple Customer Classes: One Bottleneck Station

, 2004
The paper studies a closed queueing network containing two types of node. The first type (server station) is an infinite server queueing system, and the second type (client station) is a single server queueing system with autonomous service, i.e.
Abramov, Vyacheslav M.
core   +1 more source

HMMER web server: 2018 update

Nucleic Acids Res., 2018
The HMMER webserver [http://www.ebi.ac.uk/Tools/hmmer] is a free-to-use service which provides fast searches against widely used sequence databases and profile hidden Markov model (HMM) libraries using the HMMER software suite (http://hmmer.org).
Simon C. Potter, Aurélien Luciani, S. Eddy, Y. M. Park, R. Lopez, R. Finn   +5 more
semanticscholar   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source