Results 31 to 40 of about 496,830 (322)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Improving the Public’s Health Through Sustained, Multidisciplinary Academic and Community Partnerships: The MSM Model

Journal of the Georgia Public Health Association, 2020
Background: To meet the growing needs of communities with increased chronic conditions, decreased access to health services, and a changing sociocultural environment, there is a critical need for community-oriented physicians equipped with the skills to ...
Desiree Rivers, Carla Durham Walker, Ashley Mitchell, Shirleta Lawrence, Carey Bayer   +4 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Service-learning

Education + Training, 2019
Purpose The purpose of this paper is to test whether engaging in course service-learning projects can impact interpersonal oral communication confidence and skill development beyond that of traditional course research projects. Design/methodology/approach Three sections of a university management course were randomly assigned to have a service ...
openaire   +2 more sources

Promotion of Meaning in Life and Wellbeing Among University Students During the COVID-19 Pandemic via a Service-Learning Subject

Frontiers in Public Health, 2022
Utilizing the principle of “learning by doing,” service-learning (SL) course provides a platform for university students to apply academic knowledge in serving the community, reflecting on the serving experiences, deepening their understanding of the ...
Xiaoqin Zhu, Wenyu Chai, Daniel T. L. Shek, Li Lin   +3 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Holyoke Visible: A Public Art Project in Holyoke, Massachusetts

Michigan Journal of Community Service Learning
None
Joseph Krupczynski
doaj   +2 more sources

Service-Learning as Global Citizenship Education: Acting Locally on Global Challenges and Concerns

IAFOR Journal of Education, 2020
Service-learning is a method of teaching that is increasingly used in higher education. Studies are few though on how local placements in service-learning can bring about global citizenship and promote social justice.
Genejane M. Adarlo
doaj   +1 more source

Impact of Service-Learning on Student Counselors’ Self-Reported Measures of Program Evaluation, Counselor Advocacy, and Interprofessional Education

Teaching and Supervision in Counseling, 2022
Academic service-learning encompasses a reciprocal relationship among university and community partners. Service-learning can familiarize student counselors with future client populations, community resources, and other service providers.
Jessica Lloyd-Hazlett , Cory Knight , Emily Horton, Samantha Airhart-Larraga   +3 more
doaj   +1 more source