Results 101 to 110 of about 11,676,712 (286)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
National Crystallography Service (NCS) Grid Service
, 2004 Conference poster about the NCS Grid Service.The EPSRC funded National Crystallography Service (NCS) is a facility available to the entire UK academic Chemistry community. The EPSRC funds a team of experts and 'state of the art' instrumentation, based in
Bingham, Ann +10 more
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Faculty newsletter (Vol. 4, Iss. 1)
, 2016 https://commons.ln.edu.hk/osl_faculty_news/1008/thumbnail ...
Office of Service-Learning, Lingnan University
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Service Semantics Classification: an Approach Towards Modular Service Ontology [PDF]
, 2009 Since service systems are becoming increasingly complex in emerging technology, business, legal and economics environments, service abstractions are necessary to master this complexity.
Ferreira Pires, Luis +3 more
core +1 more source
A Model of Three-Dimensional Lattice Gravity
, 1992 A model is proposed which generates all oriented $3d$ simplicial complexes weighted with an invariant associated with a topological lattice gauge theory.
Kopenhagen Ø Denmark +2 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
服務研習通訊第二十二期 Office of Service-Learning Newsletters, Volume 22
, 2017 嶺南大學服務研習處一直努力通過與學系及社區夥伴的緊密合作，為學生提供平台實踐所學，並以專業知識回應社會不同議題。服務研習做就個人成長，促進社會和諧進步。它既帶給同學們及社會正能量，也構成我們堅守使命的動力! 2017 年，是嶺南大學推行服務研習的第十一個年頭。今期【嶺召】為大家帶來六個故事，透過八位學生及畢業生在服務研習經歷中的點滴和感想，我們盼望能與您一起見證服務研習為他們帶來的成長歷程。我們亦想將這份盼望延續，願服務研習能伴您同行，編寫出另一個屬於您的成長故事!
Office of Service-Learning, Lingnan University
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Service and price competition when customers are naive
, 2012 We consider a system of two service providers each with a separate queue. Customers choose one queue to join upon arrival and can switch between queues in real time before entering service to maximize their spot utility, which is a function of price and ...
JIANG, Li, LI, Li, LIU, Liming
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source