PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Bi-Objective Optimization for Energy Aware Internet of Things Service Composition
IEEE Access, 2018 In recent years, service-oriented-based Internet of Things (IoT) has received massive attention from research and industry. Integrating and composing smart objects functionalities or their services is required to create and promote more complex IoT ...
Osama Alsaryrah +2 more
doaj +1 more source
A Quality-of-Service-Aware Service Composition Method in the Internet of Things Using a Multi-Objective Fuzzy-Based Hybrid Algorithm. [PDF]
Sensors (Basel), 2023 Hamzei M +2 more
europepmc +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Dianxin kexue, 2016 In the process of increasing the number of work-flow services, as the potential cost of the initial planning is high, and the reliability of many service composition algorithms is not enough.
Hua WEN
doaj
A Systematic Literature Review on Service Composition for People with Disabilities: Taxonomies, Solutions, and Open Research Challenges. [PDF]
Comput Intell Neurosci, 2023 Namoun A +5 more
europepmc +1 more source
A Survey on Service Composition Middleware in Pervasive Environments [PDF]
, 2009 The development of pervasive computing has put the light on a challenging problem: how to dynamically compose services in heterogeneous and highly changing environments? We propose a survey that defines the service composition as a sequence of four steps:
Ibrahim, Noha, Le Mouel, Frederic
core +3 more sources
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Dynamic QoS/QoE-aware reliable service composition framework for edge intelligence. [PDF]
Cluster Comput, 2022 Hayyolalam V, Otoum S, Özkasap Ö.
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source