Results 41 to 50 of about 125,581 (263)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Cyber‐physical description and CPS‐based pinning approach of mixed traffic
IET Intelligent Transport Systems, 2022 In this paper, a cyber‐physical description of mixed traffic that can reflect the interaction between vehicles is first proposed. By treating vehicles as nodes and the cyber‐physical interaction between vehicles as directed edges between nodes, the ...
Zhongcheng Liu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Cloud computing service value: A message to the board
South African Journal of Business Management, 2012 This paper aims to alert the board to their duty of adding value to the organizations they represent by recognizing opportunities presented by new developments in information technology.
R. Von Solms, M. Viljoen
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
AI temporal planning for energy smart buildings
Energy Informatics, 2023 Buildings are responsible for about one-third of industrialised countries’ overall energy consumption and greenhouse gas emissions. As if this was not enough, recently, energy prices significantly increased and affected all economic areas.
Ilche Georgievski +2 more
doaj +1 more source
Cloud Computing -- Everything As A Service
CoRR, 2022 Compute infrastructure hosted by a cloud provider allows an application to scale without limit. The application developer no longer needs to worry about the up-front investment in a server farm provisioned for a worst-case load scenario. However, managing cloud deployments requires a sophisticated framework that can autoscale the infrastructure and ...
openaire +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Computing as a service pattern based on edge computing
Dianzi Jishu Yingyong, 2019 Edge computing is a computational model for all terminal devices from cloud to edge path, which emerges in the era of interconnection of all things. The existing server pattern under cloud computing model cannot satisfy the application requirements of ...
Wang Tengfei +5 more
doaj +1 more source