Results 71 to 80 of about 1,160,010 (271)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

SH: Service-oriented system for HTN planning in real-world domains

open access: yesSoftwareX
SH is an open-source and domain-independent system for Hierarchical Task Network (HTN) planning, a branch of Artificial Intelligence Planning and Scheduling.
Ilche Georgievski   +3 more
doaj   +1 more source

Electronic Discovery in the Cloud [PDF]

open access: yes, 2011
Cloud Computing is poised to offer tremendous benefits to clients, including inexpensive access to seemingly limitless resources that are available instantly, anywhere.
Araiza, Alberto G.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Service migration of heterogeneous cloud computing platform

open access: yes物联网学报, 2020
With the rapid development of 5G communication technology,Internet+ and the Internet of things (IoT),cloud computing as an Internet-based virtual resource management and a distributed computing technology,provides services to users in a dynamic,on-demand
Feng WEI   +5 more
doaj   +2 more sources

Improved Crowd Counting Method Based on Scale-Adaptive Convolutional Neural Network

open access: yesIEEE Access, 2019
Crowd counting is a challenging task due to the influence of various factors, such as scene transformation, complex crowd distribution, uneven illumination, and occlusion.
Jun Sang   +6 more
doaj   +1 more source

Managing Service-Heterogeneity using Osmotic Computing

open access: yes, 2017
Computational resource provisioning that is closer to a user is becoming increasingly important, with a rise in the number of devices making continuous service requests and with the significant recent take up of latency-sensitive applications, such as ...
Jayakody, Dushantha Nalin K.   +4 more
core  

Supporting Dynamic Service Composition at Runtime based on End-user Requirements [PDF]

open access: yes, 2009
Network-based software application services are receiving a lot of attention in recent years, as observed in developments as Internet of Services, Software as a Service and Cloud Computing.
Ferreira Pires, Luis   +2 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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