Results 41 to 50 of about 4,749,039 (274)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Service dogs for autistic children and family system functioning: a constant comparative analysis
Frontiers in Psychiatry, 2023 IntroductionService dog placements for autistic children are growing in popularity, yet findings to date are mixed. Moreover, no study to date has examined these placements through the lens of a recognized theoretical model.
Sarah C. Leighton +3 more
doaj +1 more source
Domestic dog attacks on sheep in the urban fringe areas of Perth, Western Australia [PDF]
, 2002 In common with many cities, Perth, Western Australia has a problem with domestic dogs attacking livestock, such as sheep on its urban fringe areas. The current study used multiple sources to document 1479 attacks on livestock on 1105 properties by 1900 ...
Jennens, Garth
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
European Journal of Investigation in Health, Psychology and Education(1) Background: Animals provide many benefits in children’s lives, but few studies assess the effects of animal presence—especially service dogs—in schools.
Manon Toutain +3 more
doaj +1 more source
Certified service dogs - A cost-effectiveness analysis appraisal.
PLoS ONE, 2019 IntroductionIndividuals with functional impairments or chronic diseases are often in need of assistance in their daily lives. For these individuals it is essential to find novel, cost-effective solutions to meet their needs.
Martina Lundqvist +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Cripping Girlhood on Service Dog Tok
SocietiesThis article explores how disabled girl handlers crip girlhood on service dog tok, the emergent subculture on TikTok comprised of disabled handlers who upload and post videos about their everyday life in partnership with a service dog.
Anastasia Todd
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source