Results 41 to 50 of about 4,787,704 (257)

Socio‐economic evaluation of human–dog coexistence: A 40,000 years history

Veterinary Medicine and Science
The human–animal relationship and its benefits have been a popular issue in recent decades. This study focuses on the dog as a paradigmatic example of this complex bond.
Mohammad Fallahi, Ali Akbar Masoudi, Rasoul Vaez Torshizi, Ali Maghsoudi   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Working qualities of search dogs of German and Belgian shepherd breeds

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Гжицького. Серія: Сільськогосподарські науки, 2020
The main tasks for which canine units of law enforcement agencies of Ukraine use search dogs are: inspection of various areas and search operations to identify persons who have committed or intend to commit offenses, their odors and things, detection of ...
S. V. Serkhovets, N. P. Mazur, A. V. Dymchuk   +2 more
doaj   +1 more source

Case Distribution, Sources, and Breeds of Dogs Presenting to a Veterinary Behavior Clinic in the United States from 1997 to 2017

Animals, 2022
The purpose of this retrospective case study was to evaluate trends over time in case distribution, sources, and breeds of dogs presenting to the behavioral medicine service at a veterinary college referral hospital in the United States.
Katherine H. Anderson, Yufan Yao, Pamela J. Perry, Julia D. Albright, Katherine A. Houpt   +4 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Psychosocial Well-Being in Families of Autistic Children and Effect of Service Dogs: An Exploratory Study

Pets
Service dogs (SDs) have been shown to provide multi-faceted benefits for autistic children, with some benefits also extending to family members. The main objectives of this study were to explore the relationships between psychosocial well-being, family ...
Nicolas Dollion, Jennifer R. Babka, Kelly E. Pollock, Julie A. Stilley, Marine Grandgeorge, Gretchen Carlisle   +5 more
doaj   +1 more source

Visual diagnosis of internal tumors of dogs and cats in Samarkand [PDF]

BIO Web of Conferences
In this article, is provided the importance and effectivity using visual diagnostic methods in the practice of veterinary oncology for the purpose of early diagnosis and treatment of tumors as ultrasound and X-ray and also blood morphological biochemical
Yulchiyev Jasurbek, Norboyev Kurbon, Mirzayev Tursun   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

The PAWS project – Promoting and supporting the wellbeing of undergraduate students with service dogs

Human-Animal Interactions
There is growing concern for young peoples’ mental health nationally and internationally, with third-level students identified as a high-risk group for mental health difficulties.
Anna Donnla O’Hagan, Nathan Gavigan, Hannah Goss   +2 more
doaj   +1 more source

The impact of service and hearing dogs on health-related quality of life and activity level: a Swedish longitudinal intervention study

BMC Health Services Research, 2018
Background Individuals with severe disability often require personal assistance and help from informal caregivers, in addition to conventional health care.
Martina Lundqvist, Lars-Åke Levin, Kerstin Roback, Jenny Alwin   +3 more
doaj   +1 more source