Results 61 to 70 of about 4,787,704 (257)

A survey of the impact of owning a service dog on quality of life for individuals with physical and hearing disability: a pilot study

open access: yesHealth and Quality of Life Outcomes, 2017
Background Quality of life refers to a person’s experienced standard of health, comfort and happiness and is typically measured using subjective self-report scales.
Sophie S. Hall   +3 more
doaj   +1 more source

Do domestic dogs learn words based on humans’ referential behaviour? [PDF]

open access: yes, 2014
Some domestic dogs learn to comprehend human words, although the nature and basis of this learning is unknown. In the studies presented here we investigated whether dogs learn words through an understanding of referential actions by humans rather than ...
Tempelmann, Sebastian   +12 more
core   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

The effect of service dogs on veterans’ romantic partners and relationships: A preliminary mixed-methods study

open access: yesHuman-Animal Interactions
Romantic partners are often key supports for veterans diagnosed with posttraumatic stress disorder (PTSD). However, a PTSD diagnosis among veterans is often associated with lower relationship satisfaction and quality.
Williamson L.   +4 more
doaj   +1 more source

Dogs catch human yawns [PDF]

open access: yes, 2008
This study is the first to demonstrate that human yawns are possibly contagious to domestic dogs (Canis familiaris). Twenty-nine dogs observed a human yawning or making control mouth movements.
Shepherd, Alex J.   +5 more
core   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra   +5 more
wiley   +1 more source

Understanding the Diversity of Consumer Experiences with Navigating Canada’s Service Dog Industry

open access: yesSocial Sciences
The lack of publicly available demographic and prevalence data on service dog (SDog) teams in Canada challenges our understanding of how and to what degree limited industry regulations, unharmonized standards, differing pathways to acquiring an SDog, and
Linzi Williamson   +5 more
doaj   +1 more source

Trilostane in dogs [PDF]

open access: yes, 2010
Over the last 10 years, trilostane, a competitive inhibitor of steroid synthesis, is being widely used for the treatment of canine hyperadrenocorticism.
Ramsey, I.K.
core   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan   +7 more
wiley   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab   +19 more
wiley   +1 more source

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