Results 61 to 70 of about 5,348,294 (244)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Can we continue research in splenectomized dogs? Mycoplasma haemocanis: Old problem - New insight [PDF]

, 2004
We report the appearance of a Mycoplasma haemocanis infection in laboratory dogs, which has been reported previously, yet, never before in Europe. Outbreak of the disease was triggered by a splenectomy intended to prepare the dogs for a hemorrhagic shock
Muenzing, S., Packert, K., Thein, E., Messick, J. B., Schropp, A., Meisner, F., Enders, G., Wojtczyk, C., Mueller, W., Messmer, K., Kemming, Gregor, Kisch-Wedel, Hille   +11 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Veterans with Service, Emotional Support, and Companion Dogs: Examining the Relationship Between Demographics, Health Characteristics, and Intensity of Human–Dog Relationships

Behavioral Sciences
Dog ownership may be an effective nonpharmacological, rehabilitative approach to improve veterans’ mental health and well-being. For three functional types of dogs—service, emotional support, and companion—little is known about the demographic and health
Cheryl A. Krause-Parello, Christine Spadola, Jacquelyn Baldwin, Joy Sessa, Erika Friedmann   +4 more
doaj   +1 more source

Origin and Development of Service Cynology in Modern Ukraine

Law and Safety, 2020
The history of the origin and formation of service cynology in Ukraine has quite interesting aspects. First of all, at the time when the territory of modern Ukraine was part of the Russian Empire, and eventually the Soviet Union, the police service ...
V. S. Seliukov
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Human Analogue Safe Haven Effect of the Owner: Behavioural and heart rate responses to conflict situations in dogs [PDF]

, 2013
The secure base and safe haven effects of the attachment figure are central features of the human attachment theory. Recently, conclusive evidence for human analogue attachment behaviours in dogs has been provided, however, the owner’s security ...
Gácsi, Márta, Faragó, Tamás, Sernekvist, S., Tóthné Maros, Katalin   +3 more
core   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Cripping Girlhood on Service Dog Tok

Societies
This article explores how disabled girl handlers crip girlhood on service dog tok, the emergent subculture on TikTok comprised of disabled handlers who upload and post videos about their everyday life in partnership with a service dog.
Anastasia Todd
doaj   +1 more source