Results 41 to 50 of about 479,436 (269)

Near-infrared responsive polycaprolactone coatings for magnesium implants: Photodynamic antibacterial and controllable dissolution

Journal of Magnesium and Alloys
Magnesium implants have received widespread attention in orthopaedic surgery. However, the mechanical degradation and concurrent inflammation caused by the rapid corrosion of Mg limits their applications.
Xi Liu, Jinglong Pan, You Lv, Xu Wang, Xiaoze Ma, Xinxin Zhang, Guangyi Cai, Zehua Dong   +7 more
doaj   +1 more source

The role of emotions and perceived control in the recovery strategy of service companies

Apstract: Applied Studies in Agribusiness and Commerce, 2009
The purpose of this study is to investigate the effectiveness of service recovery tactics. The reseach included a qualitative study based on 30 interviews with customers and employees of a telecommunication company.
Krisztina Kolos, Zsófia Kenesei
doaj   +1 more source

What went right and what went wrong in my cellar door visit? A worldwide analysis of TripAdvisor’s reviews of Wineries & Vineyards

Wine Economics and Policy, 2022
The purpose of this work is to study the issues of service quality and service failure during visits to cellar doors in the five regions where wine tourism is most developed: Hunter Valley (AU), Mendoza (AR), Napa Valley (the USA), Stellenbosch (ZA), and
Elena Barbierato, Iacopo Bernetti, Irene Capecchi   +2 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Adaptive Servo‐Ventilation for Glottic Closure in a Patient With Adult‐Onset Congenital Central Hypoventilation Syndrome: A Case Report

Respirology Case Reports
Congenital central hypoventilation syndrome (CCHS) is a rare disorder characterised by autonomic dysfunction and typically presents in infancy, although adult‐onset disease is increasingly recognised. We report a genetically confirmed case of adult‐onset
Sushil Agwan, Saul McWhae, Krishna Bajee Sriram   +2 more
doaj   +1 more source

Impacto de una intervención educativa estructurada en las actitudes y la práctica de la insuficiencia cardiaca en Latinoamérica

Archivos de Cardiología de México
Objetivo: La implementación de las guías de insuficiencia cardiaca (IC) en la práctica real rara vez es adecuada y la mayoría de los pacientes no reciben tratamientos óptimos.
Lucrecia M. Burgos, María P. Duczynski, María L. Coronel, Jorge Thierer   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Endothelial biomarkers (Von willebrand factor, BDCA3, urokinase) as predictors of mortality in COVID-19 patients: cohort study

BMC Pulmonary Medicine
Background SARS-CoV-2 is a systemic disease that affects endothelial function and leads to coagulation disorders, increasing the risk of mortality.
Rocío Nayeli Sánchez-Santillán, Martha Patricia Sierra-Vargas, Dulce González-Islas, Octavio Gamaliel Aztatzi-Aguilar, Rogelio Pérez-Padilla, Arturo Orea-Tejeda, Yazmín Debray-García, Manolo Ortega-Romero, Candace Keirns-Davis, Alejandra Loaeza-Roman, Alejandra Rios-Pereda   +10 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Clinical service organisation for heart failure [PDF]

, 2000
Chronic heart failure (CHF) is a serious, common condition associated with frequent hospitalisation. Several different disease management interventions (clinical service organisation interventions) for patients with CHF have been proposed.To assess the effectiveness of disease management interventions for patients with CHF.We searched: Cochrane CENTRAL
S, Taylor, J, Bestall, S, Cotter, M, Falshaw, S, Hood, S, Parsons, L, Wood, M, Underwood   +7 more
openaire   +2 more sources