Results 71 to 80 of about 333,974 (259)

Precise service level agreements [PDF]

open access: yesProceedings. 26th International Conference on Software Engineering, 2004
James Skene   +2 more
openaire   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

ZSM Framework for Autonomous Security Service Level Agreement Life-Cycle Management in B5G Networks

open access: yesFuture Internet
In the rapidly evolving landscape of telecommunications, the integration of commercial 5G solutions and the rise of edge computing have reshaped service delivery, emphasizing the customization of requirements through network slices.
Rodrigo Asensio-Garriga   +6 more
doaj   +1 more source

SLA-Based Sharing Economy Service with Smart Contract for Resource Integrity in the Internet of Things

open access: yesApplied Sciences, 2019
Recently, technology startups have leveraged the potential of blockchain-based technologies to govern institutions or interpersonal trust by enforcing signed treaties among different individuals in a decentralized environment.
Lei Hang, Do-Hyeun Kim
doaj   +1 more source

Internet of Things for Mental Health: Open Issues in Data Acquisition, Self-Organization, Service Level Agreement, and Identity Management. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Gutierrez LJ   +6 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Performance and cost analysis of all-optical switching: OBS and OCS [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2011
This paper presents a study of performance and cost analysis of optical circuit switching (OCS) and optical burstswitching (OBS) by proposing the clear images of their node architectures and cost formulations.
Ekularn Dhavarudha   +2 more
doaj  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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