Results 71 to 80 of about 54,878 (303)

Service level agreements-driven management of distributed applications in cloud computing environments [PDF]

, 2015
Advancements in cloud computing have enabled the proliferation of distributed applications, which require management and control of multiple services.
Antonescu, Alexandru-Florian
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Modeling and Management of Service Level Agreements for Digital Video Broadcasting(DVB) Services

, 2007
This paper describes a metamodeling strategy of Service Level Agreements for Digital Video Broadcasting services based on the Service Level Agreement Language(SLAng).
Tlhong, Thapelo, Reeve, Jeff
core  

Flexible and dynamic SLAs management in Service Oriented Architectures

, 2011
The increasing adoption of service oriented architectures across different administrative domains forces service providers to use effective mechanisms and strategies of resource management in order for them to be able to guarantee the quality levels ...
Orazio Tomarchio, Giuseppe Di Modica, Di Modica G, Tomarchio O   +3 more
core   +1 more source

Green PON Deployment: Enhancing Performance and Sustainability Using SLA-Aware DBWA Algorithms for 25G/50G-EPON

IEEE Access
Emerging applications such as extreme virtual reality, enterprise access, 5G front-haul / back-haul, and future 6G immersive services demand exceptional bandwidth and low latency.
Sukriti Garg, Noemi Merayo
doaj   +1 more source

Flexibility-Based Energy and Demand Management in Data Centers: A Case Study for Cloud Computing

Energies, 2019
The power demand (kW) and energy consumption (kWh) of data centers were augmented drastically due to the increased communication and computation needs of IT services. Leveraging demand and energy management within data centers is a necessity.
Robert Basmadjian
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

SLAng: A language for defining service level agreements

, 2003
. Application or web services are increasingly being used across or-ganisational boundaries. Moreover, new services are being introduced at the net-work and storage level.
Lamanna, DD, Skene, J, Wolfgang Emmerich, D. Davide Lamanna, James Skene, Emmerich, W   +5 more
core  

Service Level Agreements for Cloud Computing

, 2011
Service Level Agreements for Cloud Computing provides a unique combination of business-driven application scenarios and advanced research in the area of service-level agreements for Clouds and service-oriented infrastructures.
Theilmann, Wolfgang, Butler, Joe M., Wieder, Philipp, Yahyapour, Ramin   +3 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source