Results 121 to 130 of about 13,113,594 (311)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Health Service Executive national operational plan 2013 implementing the national service plan 2013 [PDF]

open access: yes, 2013
The Health Service Executive’s National Service Plan 2013 (NSP2013), approved by the Minister on 9th January 2013, sets out the type and volume of services to be delivered by the Executive in 2013 and is informed by the Department of Health’s (DoH ...
Health Service Executive (HSE), Corporate Planning and Corporate Performance Directorate
core  

Metallurgy-inspired multi-modal design and interfacial strengthening of heterogeneous lattice structures for superior compressive performance

open access: yesMaterials & Design
Inspired by the synergistic strengthening mechanisms of heterogeneous grain structures in metallurgy, this study proposes a novel multi-modal design strategy that integrates global architectural layout design with local interfacial strengthening.
Beiouyang Chen   +4 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Improving Ride Comfort in Heavy-Duty Vehicles Through Performance-Guaranteed Control of Active Seat Suspension

open access: yesApplied Sciences
To enhance riding comfort for drivers of heavy-duty vehicles, this paper introduces a novel adaptive prescribed performance control (APPC) for active seat suspension systems.
Jian Chen, Dongyang Xi, Wen Hu, Yang Wu
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Microstructure-soft magnetic manipulation in FeSiB amorphous/nanocrystalline alloys via laser-beam powder bed fusion and rapid annealing

open access: yesVirtual and Physical Prototyping
Laser-beam powder bed fusion (LPBF) offers a highly promising approach for manufacturing Fe-based soft magnetic alloys with amorphous/nanocrystalline microstructure and customised geometries. Unfortunately, the non-equilibrium solidification behaviour of
Xiong Yao   +5 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

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