Results 51 to 60 of about 192,726 (305)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

QoS Prediction for Mobile Edge Service Recommendation With Auto-Encoder

open access: yesIEEE Access, 2019
In the mobile edge computing environment, there are a large number of mobile edge services which are the carriers of various mobile intelligent applications. So how to recommend the most suitable candidate from such a huge number of available services is
Yuyu Yin   +5 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Trust expansion and listwise learning-to-rank based service recommendation method

open access: yesTongxin xuebao, 2018
In view of the problem of trust relationship in traditional trust-based service recommendation algorithm,and the inaccuracy of service recommendation list obtained by sorting the predicted QoS,a trust expansion and listwise learning-to-rank based service
Chen FANG   +3 more
doaj   +2 more sources

Location-Aware Deep Interaction Forest for Web Service QoS Prediction

open access: yesApplied Sciences
With the rapid development of the web service market, the number of web services shows explosive growth. QoS is an important factor in the recommendation scene; how to accurately recommend a high-quality service for users among the massive number of web ...
Shaoyu Zhu, Jiaman Ding, Jingyou Yang
doaj   +1 more source

A Hybrid Approach to Service Recommendation Based on Network Representation Learning

open access: yesIEEE Access, 2019
Network representation learning has attracted much attention as a new learning paradigm to embed network vertices into a low-dimensional vector space, by preserving network information.
Hao Wu   +4 more
doaj   +1 more source

A Multigraph Approach for Web Services Recommendation

open access: yes, 2016
In this paper, we describe a Web services recommendation approach where the services’ ecosystem is represented as a heterogeneous multigraph, and edges may have different semantics. The recommendation process relies on clustering techniques to suggest services “of interest” to a user.
Fatma Slaimi   +3 more
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Service Recommendation Method Based on Trusted Similar User [PDF]

open access: yesJisuanji gongcheng, 2016
It is increasingly important to perform service recommendation as increasingly more users and services are involved in service computing,but some inauthentic service evaluations from a few users decrease the dependability and effectiveness of service ...
WU Wenming,LIU Xiping
doaj   +1 more source

Service Quality of a Public Library:

open access: yesMaketingu Janaru, 2023
The purpose of this study is to examine (1) the dimensions of perceived service quality, (2) the effect of service quality on overall satisfaction, loyalty, and recommendation, and (3) the moderating effects of age and gender on the relationship between ...
Hanako Majima
doaj   +1 more source

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