Results 171 to 180 of about 185,526 (278)

Design and Characterization of DX‐Tile DNA Nanostar‐Based Hydrogels

Advanced Science, EarlyView.
In this study, the authors demonstrated that DNA DX‐tile‐based multi‐arm motifs can be used to assemble pure DNA hydrogels, offering greater design flexibility and enhanced control over their mechanical properties and functionalization capabilities compared to single duplex‐based DNA hydrogels.
Dylan V. Scarton, Alessandra B. Coogan, Peter M. Touma, Eray O. Tulun, Katie A. Harrison, Jack Buchen, Richard C. Steiner, Christopher R. Fellin, Hunter G. Mason, Chih‐Hsiang Hu, Sally Farag, Xiaoning Yuan, Shailly Jariwala, Remi Veneziano   +13 more
wiley   +1 more source

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

Public acceptance of cybernetic avatars in the service sector: evidence from a large-scale survey. [PDF]

Front Robot AI
Aymerich-Franch L, Taha T, Miyashita T, Kamide H, Ishiguro H, Dario P.   +5 more
europepmc   +1 more source

Peptide Sequence Programmed Piezoelectric Response by Supramolecular Self‐Assembly

Advanced Science, EarlyView.
In this study, hydrophobic tripeptides are explored as building blocks for stable piezoelectric crystals. Tripeptides with phenylalanine at the central position self‐assembled into uniform, thermally stable crystals. Piezoresponse force microscopy reveals a high effective piezoelectric coefficient of 24.0 pC N−1, attributed to asymmetric molecular ...
Xuejiao Yang, Shuaijie Liu, Honglei Lu, Yuehui Wang, Hongyue Zhang, Wei Ji, Huaimin Wang   +6 more
wiley   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Correction: Robot or human? Manoeuvring switching intention after robot service failure. [PDF]

PLoS One
Helen Lee WH, Grace Chan SH, Tang BM, Song Z.   +3 more
europepmc   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Teleoperation System for Service Robots Using a Virtual Reality Headset and 3D Pose Estimation. [PDF]

Sensors (Basel)
Ribeiro T, Fernandes E, Ribeiro A, Lopes C, Ribeiro F, Lopes G.   +5 more
europepmc   +1 more source