Results 61 to 70 of about 215,088 (264)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Design and strengthening of dual bio-inspired lattice structures based on additive manufacturing

Alexandria Engineering Journal
Lattice structures are widely studied and applied due to their excellent energy absorption capabilities. This study drew inspiration from natural structures and started from the structural form.
Tongyuan Sun, Bingzhi Chen, Deyu Yue, Dongming Li   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and energy absorption performance of gradient-Orowan synergistically strengthened lattice structures

Materials & Design
Lattice structures have attracted much attention in the engineering field due to their light weight, high specific strength, and excellent energy absorption characteristics.
Dongming Li, Long Guo, Jiasen Si, Zhihui Wang, Bingzhi Chen, Xu Zhang, Junxian Zhou   +6 more
doaj   +1 more source

Development of a Canine Rigid Body Musculoskeletal Computer Model to Evaluate Gait

Frontiers in Bioengineering and Biotechnology, 2020
BackgroundKinematic and kinetic analysis have been used to gain an understanding of canine movement and joint loading during gait. By non-invasively predicting muscle activation patterns and forces during gait, musculoskeletal models can further our ...
Nathan P. Brown, Gina E. Bertocci, Gregory J. R. States, Gwendolyn J. Levine, Jonathan M. Levine, Dena R. Howland, Dena R. Howland, Dena R. Howland   +7 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Evaluation of in-service speed performance improvement by means of FDR-AF (frictional drag reducing anti-fouling) marine coating based on ISO19030 standard. [PDF]

Sci Rep, 2021
Cho Y, Jeon KH, Lee SB, Park H, Lee I.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Effect of remelting strategy on forming mechanism of selective laser melted AlSi10Mg

Journal of Materials Research and Technology
Selective laser melting (SLM) technology is widely used in various fields for manufacturing high-precision and complex parts. However, SLMed parts still exhibit some microstructural defects.
Deyu Yue, Xu Zhang, Dongming Li, Zhuofeng Li, Zhaoyi Wang, Bingzhi Chen   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source