Results 131 to 140 of about 9,639,909 (351)

Trajectory Aware Macro-cell Planning for Mobile Users

open access: yes, 2015
We design and evaluate algorithms for efficient user-mobility driven macro-cell planning in cellular networks. As cellular networks embrace heterogeneous technologies (including long range 3G/4G and short range WiFi, Femto-cells, etc.), most traffic ...
Bhattacharya, Arnab   +6 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Optimising Capacity – A Service User and Caregiver Perspective on Reablement

open access: yesGrounded Theory Review: An International Journal, 2016
Reablement focuses on offering individuals the opportunity to regain independence and thus stay longer in their homes. Few studies have looked at service users and caregivers’ perspectives on reablement.
Cathrine Moe, Berit Støre Brinchmann
doaj  

An Optimal Application-Aware Resource Block Scheduling in LTE

open access: yes, 2014
In this paper, we introduce an approach for application-aware resource block scheduling of elastic and inelastic adaptive real-time traffic in fourth generation Long Term Evolution (LTE) systems. The users are assigned to resource blocks.
Abdelhadi, Ahmed   +2 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

A Modified Decision Tree Algorithm Based on Genetic Algorithm for Mobile User Classification Problem

open access: yesThe Scientific World Journal, 2014
In order to offer mobile customers better service, we should classify the mobile user firstly. Aimed at the limitations of previous classification methods, this paper puts forward a modified decision tree algorithm for mobile user classification, which ...
Dong-sheng Liu, Shu-jiang Fan
doaj   +1 more source

Intelligent protocol adaptation for enhanced medical e-collaboration [PDF]

open access: yes, 2003
Copyright @ 2003 AAAIDistributed multimedia e-health applications have a set specific requirements which must be taken into account effective use is to be made of the limited resources provided by public telecommunication networks.
Frank, AO, Ghinea, G, Magoulas, GD
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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