Results 101 to 110 of about 16,976 (295)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Vibration serviceability considerations in footbridge design. [PDF]
, 2011 Modern footbridges are becoming more and more flexible as they are constructed lighter and more slender than ever before. This has led to a vibration serviceability issue with many footbridges, as they can become ‘lively’ by pedestrians simply ...
Archbold, Paul, Mullarney, Brian
core
Modal testing and FE model tuning of a lively footbridge structure [PDF]
, 2006 Despite huge advances in numerical modelling of civil engineering structures in recent decades, finite element models for footbridges should still be developed and used with caution when evaluating modal properties of these structures.
Pavić, Aleksandar +2 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Serviceability assessments of masonry arch bridges [PDF]
Masonry arch bridges continue to play an important role in the UK's transport infrastructure, forming a significant proportion of road, rail and waterway crossings.
Wu, Lufang
core
LandAssessing urban green spaces’ (UGSs) serviceability is crucial for ecosystems and well-being, but traditional approaches focus only on the quantity of UGSs while neglecting their spatial configuration or depend on region-specific data sources ...
Yuetong Qin +4 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Structural safety and usability evaluation of one way voided slab with Formwork
Journal of Asian Architecture and Building EngineeringThis study proposed a formwork-integrated hollow slab with an improved shape made of a hollow material. The performance of the proposed formwork-integrated hollow slab was evaluated through flexural and shear tests.
Moowon Hur, Hyun-Ho Lee, Taewon Park
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source