Results 111 to 120 of about 16,976 (295)

Fuzzy Logic Approach for Serviceability Evaluation

, 1996
Serviceability evaluation during early design stages is a process of evaluating the product design in terms of ease of service or maintenance during a product usage life cycle.
Wang, Jiangping, Allada, Venkat
core  

Serviceability criteria for design of timber floors [PDF]

, 2018
This paper summarizes current regulations for comfort assessment of structural vibrations of timber floors in Europe and main design practices of timber floors on this aspect among the European countries.
Bešević, Miroslav, Kozarić, Ljiljana, Tekić, Žikica, Vojnić Purčar, Martina, Živković, Smilja   +4 more
core  

Parametric Analysis of Moment-Resisting Timber Frames Combined with Cross Laminated Timber Walls and Prediction Models Using Nonlinear Regression and Artificial Neural Networks

Buildings
The light weight and moderate stiffness of multistorey timber buildings make them susceptible to increased lateral displacements and accelerations under service-level wind loading.
Osama Abdelfattah Hegeir, Haris Stamatopoulos, Kjell Arne Malo   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Complex verification of the road pavement serviceability

, 1982
As a part of the scientific-technical co-operation between Finland and Hungary problems connected with pavement serviceability and pavement condition evaluation have been dealt with.
Gaspar, Laszlo, Lampinen, Anssi
core  

Variable Serviceability Concept for Pavement Design Confirmed by AASHO Road Test Fatigue Data

, 1984
Fatigue data from the AASHO Road Test were plotted for each level of serviceability. The Kentucky thickness design system uses the concept of a variable level of serviceability as a function of EALs. The Kentucky thickness design curve for the equivalent
Deen, Robert C., Southgate, Herbert F.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source