Results 131 to 140 of about 23,563 (273)

The Effect of Pedestrian Traffic on the Dynamic Behavior of Footbridges

open access: yesActa Polytechnica, 2004
The dynamic response of a footbridge depends namely on the natural frequencies of the structure in vertical, in horizontal and in torsion. If any of the frequencies in vertical is in the range 1.0 Hz to 3.0 Hz, the dynamic response from moving people can
M. Studničková
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Experiments with Externally Prestressed Continuous Composite Girders

open access: yesActa Polytechnica, 2001
Steel-concrete composite girders have attractive potentials when applied in bridge construction. The serviceability performance of continuous composite girders is becoming more and more a deterministic parameter in the design of this type of structures ...
M. Safan, A. Kohoutková
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Glass Serviceability Limits

open access: yes
The performance of the building envelope of a building is crucial for minimizing operational carbon emissions and maintaining indoor comfort. Contemporary building envelopes, such as highly engineered glazed façades, achieve high performance levels but ...
Pedro de la Barra   +5 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

LEAN MAINTENANCE FRAMEWORK FOR ARMY VEHICLES SERVICEABILITY

open access: yes
Serviceability refers to maintenance, repair activities and is imperative in all organizations. In the context of Military organizations, these maintenance activities encompass the maintenance of equipment, weapons, vehicles, electronic items and other ...
AMRAN BIN MOHAMAD NAYAN, UniKL MIDI
core  

Impact of Temporal and Spatial Resolution in Slope-Plant-Atmosphere Interaction Modelling. [PDF]

open access: yesGeotech Geol Eng (Dordr)
Maddah Sadatieh MS   +2 more
europepmc   +1 more source

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