Results 131 to 140 of about 16,976 (295)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Reliability-based serviceability limit states for concrete girder bridges
, 2013 Although ultimate limit state, such as flexural capacity, shear, or stability, governs the overall safety of the structure, the accumulated damage due to cracking, excessive deflections, and vibrations also would lead to limitation of structural ...
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The performance of the building envelope of a building is crucial for minimizing operational carbon emissions and maintaining indoor comfort. Contemporary building envelopes, such as highly engineered glazed façades, achieve high performance levels but ...
Pedro de la Barra +5 more
core
Vibration serviceability assessment of footbridges using VSATs software
, 2008 Slender structural forms have become common in contemporary design of footbridges. These structures are normally occupied and dynamically excited by humans. Their slenderness in combination with human activities such as walking, jumping and running often
Pavić, Aleksandar +2 more
core
, 2019 As the construction of long-span bridges such as cable-stayed bridges increases worldwide, maintaining bridge serviceability and operability has become an important issue in civil engineering.
Jeong, Seunghoo +2 more
core +1 more source
Information Integration Method of Product Design for Service-embedded Manufacturing
工程科学与技术, 2018 With the continuous integration of manufacturing and service industries,service plays an increasingly important role in the manufacturing industry.In order to assist designers to achieve product serviceability in the product design process,an information
Kai ZHANG, Wu ZHAO, Jie WANG, Xin GUO
doaj
A Two-Level Comparative Assessment of Concrete Building Systems and Member Typologies
BuildingsConcrete building systems require decisions at both the member and the building level, because locally efficient cross sections do not necessarily lead to a favorable whole-building response.
Abtin Baghdadi +2 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source