Results 151 to 160 of about 23,563 (273)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Collected data on displacement and vibration tests of layered floor assembly constructed by using glued timber trusses. [PDF]

Data Brief
Hatsala A, Ilgın HE, Kinnunen N, Luukkainen JP, Malmstedt F, Pajunen S, Rinkinen K, Sormunen J.   +7 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Influence of non-stationarity in friction angle on the performance of the braced excavation system. [PDF]

Sci Rep
Rafi KM, Ering P.
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Reliability-based serviceability limit states for concrete girder bridges

, 2013
Although ultimate limit state, such as flexural capacity, shear, or stability, governs the overall safety of the structure, the accumulated damage due to cracking, excessive deflections, and vibrations also would lead to limitation of structural ...

core  

Experimental Evaluation of a Concealed Anchoring System for Large-Format Thin Ceramic Panels Under Wind Loading in Ventilated Façades. [PDF]

Materials (Basel)
Roviras Miñana J, Sarrablo Moreno V, Casariego Vales P.   +2 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Time-dependent serviceability of corrosion-affected concrete structures

, 2006
Practical experience and experimental observations suggest that corrosion-affected concrete structures deteriorate at different rates as measured by strength and serviceability, with the latter deteriorating faster.
Chun Qing Li (18025120), R Melchers (20025477)   +1 more
core  

Serviceability design charts for partially prestressed high-strength concrete girders. [PDF]

Sci Rep
Salem S, Abu-Krisha M, Hassan T, El-Hashimy T.   +3 more
europepmc   +1 more source