From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Flexural behavior and crack development of reinforced geopolymer slabs with longitudinal voids: an experimental study. [PDF]
Aziz YHA, Malky AE, El-Sayed TA.
europepmc +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Wind-induced vibration serviceability of ten multi-storey timber buildings. [PDF]
Kurent B, Brank B.
europepmc +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Development of a framework to completely quantify airfield pavement serviceability
The Federal Aviation Administration proposed a new concept for measuring airport pavement condition that consolidates measures of Foreign Object Damage (FOD), skid resistance, and smoothness into a single number.
Parsons, Timothy Allen
core
Time dependent seismic fragility and serviceability assessment of reinforced concrete frames under chloride induced corrosion. [PDF]
Kordtabar B +3 more
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Serviceability design considerations for steel buildings
Diplomska naloga obravnava projektiranje jeklenih konstrukcij na mejna stanja uporabnosti v skladu s standardi Evrokod. Najprej so na splošno definirana mejna stanja nosilnosti in uporabnosti, ki jih predpisuje osnovni standard. Nato je prikazana izvedba
Bratina, Nick
core
Mechanical behavior of deteriorated unbonded prestressed concrete hollow slabs. [PDF]
Li X, Zhou S, Xiang B, Yan M, Bao Y.
europepmc +1 more source

