Results 81 to 90 of about 3,932 (298)
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi +6 more
wiley +1 more source
Vibration Serviceability Assessment for Pedestrian Bridges Based on Model Falsification
With the development of new materials and advanced structural analysis, alongside increasing aesthetic requirements, recent years have witnessed a trend toward longer, taller, and lighter footbridges.
Smith, Ian F. C. +2 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
To achieve a relatively consistent probability of failure for structural elements, most design codes apply reliability based code calibration process. Such approaches commonly focus on the ultimate strength of the structural members, which is related to ...
Honfi, Daniel, +2 more
core
Serviceability Limit State Reliability Analysis of Perniö Railway Embankment
In this paper, serviceability limit state reliability analysis of a railway embankment on soft clay is conducted using probabilistic approach. The aim of this study is to evaluate how uncertainties in soil parameters and geometry affect the reliability ...
Korkiala-Tanttu, Leena +3 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Reliability of steel flexural members according to EC in serviceability limit state
To achieve a relatively consistent probability of failure for structural elements, most design codes apply reliability based code calibration process. Such approaches commonly focus on the ultimate strength of the structural members, which is related to ...
Mårtensson, Annika, Honfi, Daniel
core

