Results 71 to 80 of about 4,167,201 (303)
Utrecht Law Review, 2012 The cost recovery of water services is becoming known as an important element for water management internationally. The Water Framework Directive is a leading document in implementing these economic instruments in the European Union and it is also a good
Liping Dai
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Statement supporting European Directive 2010/63/EU (“Directive”) on the protection of animals used for scientific purposes [PDF]
, 2014 The use of animals in research has facilitated major breakthroughs in medicine which have transformed human and animal health. We support research using animals where alternative methods are not available, where the potential benefits to health are ...
DIRECTIVE
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Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Iustitia, 2011 La interpretación de los contratos celebrados por las empresas plantea dificultades distintas de las que se producen respecto de los contratos celebrados por personas físicas.
Silvia Gema Navares González
doaj +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Systemic-Functional Approach to Utilities Supplys
Модернизация, инновация, развитие, 2017 Purpose: the purpose of the article consists in statement of management approach to development of utilities supply processes based on conflict situations decision – making search.
Nikolay I. Komkov +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Cloud Computing and Risk: A look at the EU and the application of the Data Protection Directive to cloud computing [PDF]
, 2013 The use of cloud services for the management of records presents many challenges, both in terms of the particulars of data security as well the need to sustain and ensure the greater reliability, authenticity, and accuracy of records. To properly grapple
Ostrzenski, Victoria
core +1 more source
A Spatial Data Infrastructure for the Global Mercury Observation System
E3S Web of Conferences, 2013 The Global Mercury Observation System (GMOS) Project includes a specific Work Package aimed at developing tools (i.e. databases, catalogs, services) to collect GMOS datasets, harvest mercury databases, and offer services like search, view, and download ...
Cinnirella S. +4 more
doaj +1 more source