Exploratory assessment of serological tests to determine antibody titer against SARS-CoV-2: Appropriateness and limits. [PDF]
J Clin Lab Anal, 2022 Correlation plot represents the correlation between the result of the serological tests and MILLIPLEX® SARS‐ CoV‐2 Antigen Panels. The strength of the correlation is represented by dot color and size, according to the continuous bar reported in the figure.
Colombini A +9 more
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New Insights in CaVβ Subunits: Role in the Regulation of Gene Expression and Cellular Homeostasis [PDF]
Frontiers in Cell and Developmental Biology, 2022 The voltage-gated calcium channels (CaVs or VGCCs) are fundamental regulators of intracellular calcium homeostasis. When electrical activity induces their activation, the influx of calcium that they mediate or their interaction with intracellular players
Amélie Vergnol +3 more
doaj +2 more sources
Enhancing Microbiome Research through Genome-Scale Metabolic Modeling [PDF]
mSystems, 2021 Construction and analysis of genome-scale metabolic models (GEMs) is a well-established systems biology approach that can be used to predict metabolic and growth phenotypes.
Nana Y. D. Ankrah +9 more
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RhoA Is a Crucial Regulator of Myoblast Fusion [PDF]
Cells, 2023 Satellite cells (SCs) are adult muscle stem cells that are mobilized when muscle homeostasis is perturbed. Here we show that RhoA in SCs is indispensable to have correct muscle regeneration and hypertrophy.
Chiara Noviello +6 more
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Report and Abstracts of the 18th Meeting of the Interuniversity Institute of Myology: Virtual meeting, October 21-24, 2021 [PDF]
European Journal of Translational Myology, 2021 In 2021, as the situation due to COVID-19 pandemic was still uncertain, the 18 th annual meeting of the Interuniversity Institute of Myology (IIM), took place on a virtual platform, following the same organization already tested for the previous edition.
Francesca Grassi, Sestina Falcone
doaj +2 more sources
The lncRNA 44s2 Study Applicability to the Design of 45-55 Exon Skipping Therapeutic Strategy for DMD [PDF]
Biomedicines, 2021 In skeletal muscle, long noncoding RNAs (lncRNAs) are involved in dystrophin protein stabilization but also in the regulation of myocytes proliferation and differentiation.
Elena Gargaun +20 more
doaj +2 more sources
Primary Cilia and Cardiovascular Risk Factors in Alzheimer’s Disease [PDF]
Brain SciencesAlzheimer’s disease (AD) is the most common cause of dementia worldwide due to an aging population. AD is characterized as a progressive neurodegenerative disease that leads to atrophy of brain tissue, causing cognitive deficits. Amyloid beta plaques and
Clare L. Sunderman +7 more
doaj +2 more sources
Identification of CaVβ1 Isoforms Required for Neuromuscular Junction Formation and Maintenance [PDF]
CellsVoltage-gated Ca2+ channels (VGCCs) are regulated by four CaVβ subunits (CaVβ1–CaVβ4), each showing specific expression patterns in excitable cells. While primarily known for regulating VGCC function, CaVβ proteins also have channel-independent roles ...
Amélie Vergnol +17 more
doaj +2 more sources
Hormetic Nutrition and Redox Regulation in Gut–Brain Axis Disorders [PDF]
AntioxidantsThe antioxidant and anti-inflammatory effects of hormetic nutrition for enhancing stress resilience and overall human health have received much attention.
Maria Scuto +5 more
doaj +2 more sources
miR-708-5p and miR-34c-5p are involved in nNOS regulation in dystrophic context [PDF]
Skeletal Muscle, 2018 Background Duchenne (DMD) and Becker (BMD) muscular dystrophies are caused by mutations in the DMD gene coding for dystrophin, a protein being part of a large sarcolemmal protein scaffold that includes the neuronal nitric oxide synthase (nNOS).
Marine Guilbaud +11 more
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