Results 81 to 90 of about 171,090 (289)
Active Semi-Supervised Learning Using Sampling Theory for Graph Signals
, 2014 We consider the problem of offline, pool-based active semi-supervised learning on graphs. This problem is important when the labeled data is scarce and expensive whereas unlabeled data is easily available.
Blum A. +8 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Developing an ontological sandbox : investigating multi-level modelling’s possible Metaphysical Structures [PDF]
, 2017 One of the central concerns of the multi-level modelling (MLM) community is the hierarchy of classifications that appear in conceptual models; what these are, how they are linked and how they should be organised into levels and modelled. Though there has
de Cesare, Sergio +4 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
A Novel Image Segmentation Algorithm Based on Neutrosophic Filtering and Level Set [PDF]
Neutrosophic Sets and Systems, 2016 Image segmentation is an important step in image processing and analysis, pattern recognition, and machine vision. A few of algorithms based on level set have been proposed for image segmentation in the last twenty years.
Yanhui Guo, Abdulkadir Şengür
doaj
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
A Non-invasive Method to Diagnose Lung Adenocarcinoma
Frontiers in Oncology, 2020 Purpose: To find out the CT radiomics features of differentiating lung adenocarcinoma from another lung cancer histological type.Methods: This was a historical cohort study, three independent lung cancer cohorts included.
Mengmeng Yan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Experimental Investigation for RUAV's Actuator Fault Detections with AESMF
International Journal of Advanced Robotic Systems, 2015 The adaptive extended set-membership filter (AESMF) algorithm for robots' online modelling is today proposed for use in this field. Compared to the traditional ESMF, this novel filter method improves estimation accuracy under variable boundaries of ...
Dalei Song +3 more
doaj +1 more source