Results 61 to 70 of about 99,057 (272)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Distributed networked set-membership filtering with ellipsoidal state estimations [PDF]

Information Sciences, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Xia, Nan, Yang, Fuwen, Han, Qing-Long
openaire   +3 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

A Set-Theoretic Algorithm for Real-Time Terrain Mapping of Mobile Robots in Outdoor Environments

International Journal of Advanced Robotic Systems, 2013
In this paper, we address the problem of mapping outdoor rough terrain environments for mobile robots. While uncertainties arising from multiple sources are considered explicitly and assumed to be unknown-but-bounded, a set-theoretic framework is ...
Bo Zhou, Kun Qian, Xudong Ma, Xianzhong Dai   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

An Enhanced Set-Membership PNLMS Algorithm with a Correntropy Induced Metric Constraint for Acoustic Channel Estimation

Entropy, 2017
In this paper, a sparse set-membership proportionate normalized least mean square (SM-PNLMS) algorithm integrated with a correntropy induced metric (CIM) penalty is proposed for acoustic channel estimation and echo cancellation.
Zhan Jin, Yingsong Li, Yanyan Wang
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

A Hybrid Active Filter Using the Backstepping Controller for Harmonic Current Compensation [PDF]

, 2019
This document presents a new hybrid combination of filters using passive and active elements because of the generalization in the use of non-linear loads that generate harmonics directly affecting the symmetry of energy transmission systems that ...
Ababssi, Najib, Daou, Nora, Djeghader, Yacine, Gil Montoya, Francisco   +3 more
core   +1 more source

Optimal Prediction and Update for Box Set-Membership Filter [PDF]

IEEE Access, 2019
This paper investigates a box set-membership filter for nonlinear dynamic systems and on-line usage. To the best of our knowledge, although ellipsoid set-membership filter has more freedom degree to optimize a bounding estimation, it is computationally intractable to obtain an optimal prediction and update, and the approximation loss is uncertain in ...
Fanqin Meng, Haiqi Liu, Xiaojing Shen, Junfeng Wang   +3 more
openaire   +2 more sources