Results 61 to 70 of about 98,696 (254)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Robust Reduced-Rank Adaptive Processing Based on Parallel Subgradient Projection and Krylov Subspace Techniques [PDF]
, 2013 In this paper, we propose a novel reduced-rank adaptive filtering algorithm by blending the idea of the Krylov subspace methods with the set-theoretic adaptive filtering framework.
Isao Yamada +3 more
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
, 2017 We characterize the first 40 Myr of evolution of circumstellar disks through a unified study of the infrared properties of members of young clusters and associations with ages from 2 Myr up to ~ 40 Myr: NGC 1333, NGC 1960, NGC 2232, NGC 2244, NGC 2362 ...
Gaspar, Andras +3 more
core +1 more source
Distributed networked set-membership filtering with ellipsoidal state estimations [PDF]
Information Sciences, 2018 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Xia, Nan, Yang, Fuwen, Han, Qing-Long
openaire +3 more sources
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
A Set-Theoretic Algorithm for Real-Time Terrain Mapping of Mobile Robots in Outdoor Environments
International Journal of Advanced Robotic Systems, 2013 In this paper, we address the problem of mapping outdoor rough terrain environments for mobile robots. While uncertainties arising from multiple sources are considered explicitly and assumed to be unknown-but-bounded, a set-theoretic framework is ...
Bo Zhou +3 more
doaj +1 more source
A Hybrid Active Filter Using the Backstepping Controller for Harmonic Current Compensation [PDF]
, 2019 This document presents a new hybrid combination of filters using passive and active elements because of the generalization in the use of non-linear loads that generate harmonics directly affecting the symmetry of energy transmission systems that ...
Ababssi, Najib +3 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source