Results 11 to 20 of about 97,144 (227)

Verifiable necessary and sufficient conditions for openness and regularity of set-valued and single-valued maps

Journal of Mathematical Analysis and Applications, 1988
J. Borwein, D. Zhuang
semanticscholar   +3 more sources

Finite Approximations to Quantum Physics: Quantum Points and their Bundles

, 1993
There exists a physically well motivated method for approximating manifolds by certain topological spaces with a finite or a countable set of points.
A.P. Balachandran, Aleksandrov, Aneziris, Avron, Balachandran, Balachandran, Bamonte, Bombelli, Creutz, de Gennes, Drouffe, E. Ercolessi, G. Bimonte, Hilton, Hooft, Ivashchenko, Jaffe, Kleinert, Kogut, McCoy, Munkres, P. Teotonio-Sobrinho, Parisi, Rabin, Sorkin, Sorkin, Stanley, Van Dyck   +27 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Regulous vector bundles

, 2017
Among recently introduced new notions in real algebraic geometry is that of regulous functions. Such functions form a foundation for the development of regulous geometry.
Atiyah, Benedetti, Bochnak, Bochnak, Bochnak, Bochnak, Bochnak, Fichou, Hironaka, Huisman, Huisman, Husemoller, Kollár, Kollár, Kollár, Kucharz, Kucharz, Kucharz, Kucharz, Kucharz, Kucharz, Kucharz, Kucharz, Kucharz, Kucharz, Kurdyka, Kurdyka, Marinari, Nowak, Parusiński, Serre, Swan, Swan, Zhang, Zieliński   +34 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Refinement of Novikov - Betti numbers and of Novikov homology provided by an angle valued map [PDF]

, 2016
To a pair (X,f), X compact ANR and f a continuous angle valued map defined on X, a fixed field and a nonnegative integer one assigns a finite configuration of complex numbers with multiplicities located in the punctured complex plane and a finite ...
Burghelea, D.
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Productively Lindel\"of spaces and the covering property of Hurewicz

, 2014
We prove that under certain set-theoretic assumptions every productively Lindel\"of space has the Hurewicz covering property, thus improving upon some earlier results of Aurichi and Tall.Comment: 6 ...
Repovš, Dušan, Zdomskyy, Lyubomyr
core   +1 more source