Results 151 to 160 of about 639,889 (202)

Diagnostic accuracy of ovarian cancer using convolutional neural network: a systematic review and meta-analysis. [PDF]

BMC Med Inform Decis Mak
Allahqoli L, Karimzadeh A, Kazemi Abadi A, Aghamohammadi SZ, Hakimi S, Rahmani A, Fallahi A, Salehiniya H, Laganà AS, Bhagavathula AS, Ghiyasvand M.   +10 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Standardised Transparent Orthopaedic Reporting and Modelling for AI (STORM-AI)-Guidelines for reporting artificial intelligence studies in orthopaedics from the ESSKA AI Working Group. [PDF]

J Exp Orthop
Oettl FC, Zsidai B, Yu Y, Pruneski J, Tischer T, Pareek A, Grassi A, Zaffagnini S, Hirschmann MT, Samuelsson K, ESSKA Artificial Intelligence Working Group.   +10 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Performance benchmarking of LLMs on Chinese national medical licensing education: Cross-lingual and question-type effects. [PDF]

PLoS One
Tang Y, Chen J, Wang S.
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

White Matter Tract Alterations in Bipolar Disorder: A Systematic Review and Meta-Analysis of Diffusion Tensor Imaging Studies. [PDF]

Brain Behav
Mahmoudvand B, Soleimani Meigoli MS, Mohebbi A, Namazi N, Jafari M, Saghafi MS, Yousefi M, Asadi Anar M, Rigi A, Zakavi SA, Khosravi MJ, Khosravi F, Rahimian Z, Mahdavian H, Torkzadeh H, Arab Bafrani M, Karami S, Hajizamani S, Hosseini MS.   +18 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Deep Learning-Based Analysis of Gene Expression Data and Gene-Related Information in Pediatric Surgical Oncology: A Scoping Review. [PDF]

Cancer Med
Berhe S, Fuchs SE, Akalin A, van der Steeg AFW, Warmann SW, Buser MAD, Markel M.   +6 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source