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Is diabetes associated with increased pathological burden in Alzheimer's disease?
Introduction We examined the association between Alzheimer's disease (AD) and type 2 diabetes mellitus (DM) and hypothesized that diabetes is associated with an increased pathological burden in clinically and pathologically diagnosed AD. Methods All data
Kaviyon Sadrolashrafi+6 more
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We developed a novel prediction model for recurrence and survival in patients with localized renal cell carcinoma (RCC) after surgery and a novel statistical method of machine learning (ML) to improve accuracy in predicting outcomes using a large Asian ...
Jung Kwon Kim+15 more
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A General Introduction To Graph Visualization Techniques [PDF]
Generally, a graph is an abstract data type used to represent relations among a given set of data entities. Graphs are used in numerous applications within the field of information visualization, such as VLSI (circuit schematics), state-transition ...
Ebert, Achim+2 more
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Multi-dimensional classification of GABAergic interneurons with Bayesian network-modeled label uncertainty [PDF]
Interneuron classification is an important and long-debated topic in neuroscience. A recent study provided a data set of digitally reconstructed interneurons classified by 42 leading neuroscientists according to a pragmatic classification scheme composed
Benavides-Piccione, Ruth+4 more
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CloudNet: Ground‐Based Cloud Classification With Deep Convolutional Neural Network
Clouds have an enormous influence on the Earth's energy balance, climate, and weather. Cloud types have different cloud radiative effects, which is an essential indicator of the cloud effect on radiation.
Jinglin Zhang+3 more
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scAlign: a tool for alignment, integration, and rare cell identification from scRNA-seq data
scRNA-seq dataset integration occurs in different contexts, such as the identification of cell type-specific differences in gene expression across conditions or species, or batch effect correction. We present scAlign, an unsupervised deep learning method
Nelson Johansen, Gerald Quon
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Statistical process control for data without inherent order [PDF]
Background The XmR chart is a powerful analytical tool in statistical process control (SPC) for detecting special causes of variation in a measure of quality. In this analysis a statistic called the average moving range is used as a measure of dispersion
Alan J Poots, Thomas Woodcock
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Background Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that is highly phenotypically and genetically heterogeneous. With the accumulation of biological sequencing data, more and more studies shift to molecular subtype-first ...
Junjie Zhang+3 more
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Network enrichment analysis: extension of gene-set enrichment analysis to gene networks [PDF]
Background Gene-set enrichment analyses (GEA or GSEA) are commonly used for biological characterization of an experimental gene-set. This is done by finding known functional categories, such as pathways or Gene Ontology terms, that are over-represented ...
Alexeyenko Andrey+7 more
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The aim of this study is to characterize cell type-specific transcriptional signatures in non-alcoholic steatohepatitis (NASH) to improve our understanding of the disease.
Rikard G. Fred+11 more
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