Results 31 to 40 of about 603,733 (222)
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro +10 more
wiley +1 more source
Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data
Background Microarray technology has become very popular for globally evaluating gene expression in biological samples. However, non-linear variation associated with the technology can make data interpretation unreliable.
Kulesz-Martin Molly +3 more
doaj +1 more source
The functional bootstrap for boundary CFT
We introduce a new approach to the study of the crossing equation for CFTs in the presence of a boundary. We argue that there is a basis for this equation related to the generalized free field solution. The dual basis is a set of linear functionals which
Apratim Kaviraj, Miguel F. Paulos
doaj +1 more source
Background Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that is highly phenotypically and genetically heterogeneous. With the accumulation of biological sequencing data, more and more studies shift to molecular subtype-first ...
Junjie Zhang +3 more
doaj +1 more source
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Feasibility of predicting firearm type in firearm suicide deaths for better policy evaluation
Background Imprecise firearm-type data limits capacity to evaluate firearm-type-specific policies; a striking proportion of firearm suicides in the National Vital Statistics System (NVSS) do not include information on firearm-type.
Emma L. Gause +2 more
doaj +1 more source
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman +17 more
wiley +1 more source
Distant metastasis is one of the main reasons for the failure of nasopharyngeal carcinoma (NPC) treatment, and descending type of nasopharyngeal carcinoma (type D NPC) is more prone to distant metastasis. Few people have explored the relationship between
Qin Yang +9 more
doaj +1 more source
Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy +5 more
wiley +1 more source
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk +9 more
wiley +1 more source

