Results 131 to 140 of about 504,784 (313)

Set-Covering Problem: Frank-Wolfe algorithm implementation for the linear relaxation

openIl problema del Set-Covering (Set-Covering Problem, SCP) è un problema di ottimizzazione combinatoria che consiste nel determinare la più piccola collezione di elementi in una famiglia di sottoinsiemi di un insieme, in modo che ciascun elemento di ...
CALLEGARI, LEONARDO
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Model and algorithm for forming spatially distributed groups of aerial objects to optimize their energy supply

Известия высших учебных заведений. Поволжский регион:Технические науки
Background. The object of the research is the energy supply system for spatially distributed groups of aerial objects. The subject of the research is algorithms for forming optimal clusters for simultaneous energy transmission to multiple unmanned aerial
A.A. Chepiga
doaj   +1 more source

Binary Chaotic White Shark Optimizer for the Unicost Set Covering Problem

Mathematics
The Unicost Set Covering Problem (USCP), an NP-hard combinatorial optimization challenge, demands efficient methods to minimize the number of sets covering a universe.
Pablo Zúñiga-Valenzuela, Broderick Crawford, Felipe Cisternas-Caneo, Eduardo Rodriguez-Tello, Ricardo Soto, José Barrera-Garcia, Fernando Lepe-Silva   +6 more
doaj   +1 more source

Crew Scheduling for Netherlands Railways: "destination: customer"

: In this paper we describe the use of a set covering model with additional constraints for scheduling train drivers and conductors for the Dutch railway operator NS Reizigers.
Fischetti, M., Kroon, L.G.
core  

Hierarchical location-allocation models for congested systems [PDF]

In this paper we address the issue of locating hierarchical facilities in the presence of congestion. Two hierarchical models are presented, where lower level servers attend requests first, and then, some of the served customers are referred to higher ...
Daniel Serra, Vladimir Marianov
core  

The minimal covering set in large tournaments

, 2012
We prove that in almost all large tournaments, the minimal covering set is the entire set of alternatives. That is, as the number of alternatives gets large, the probability that the minimal covering set of a uniformly chosen random tournament is the ...
Scott, A, Fey, M
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Approximation algorithms for rectangle stabbing and interval stabbing problems. [PDF]

Inthe weighted rectangle stabbing problem we are given a grid in R2 consisting of columns and rows each having a positive integral weight, and a set of closed axis-parallel rectangles each having a positive integral demand.
Kovaleva, S, Spieksma, Frederik
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source