Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj +25 more
wiley +1 more source
A Six-Tap 720 × 488-Pixel Short-Pulse Indirect Time-of-Flight Image Sensor for 100 m Outdoor Measurements. [PDF]
Itaba K +4 more
europepmc +1 more source
The interfacial stability and activity of Ni‐Fe‐based AEMWE anodes can be directly enhanced by operando voltage‐cycling in a FeOOH‐containing electrolyte. This process simultaneously induces Ni oxidation and Fe incorporation, forming an integrated, porous (Fe, Ni)OOH layer with high conductivity and durability.
Euntaek Oh +10 more
wiley +1 more source
A proteomic map of thromboinflammatory signatures in antiphospholipid syndrome: results from antiphospholipid syndrome alliance for clinical trials and international networking (APS ACTION) registry. [PDF]
Pine A +22 more
europepmc +1 more source
Aerodynamic dataset for selected doubly curved membrane canopy structures. [PDF]
Kodakkal A +9 more
europepmc +1 more source
Investigating Major Infestation Routes of Several Key Thrips Species (Thysanoptera: Thripidae) in Greenhouse-Grown Chrysanthemums in Ontario, Canada. [PDF]
Summerfield A +3 more
europepmc +1 more source
Antiphospholipid syndrome and pregnancy-a hematologic perspective. [PDF]
Doyle AJ, Cox C, Breen KA.
europepmc +1 more source
The plasmonic BTO-on-SiN platform - beyond 200 GBd modulation for optical communications. [PDF]
Kohli M +15 more
europepmc +1 more source
SlideRing: Robust Dual-IMU Thumb-to-Finger Text Input for Virtual Reality. [PDF]
Sun T, Jia N, Jiao D.
europepmc +1 more source

