Results 41 to 50 of about 21,126 (306)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

“Gilead is within you”: a theocratic narrative setting of cultural memory in Atwood’s The Testaments [version 1; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2023
This article attempts to explore the synthetic relationship between group identities and their effects on cultural memory in Margaret Atwood's The Testaments.
Palak Arora, Manshi Yadav
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Keystrokes Inference Attack on Android: A Comparative Evaluation of Sensors and Their Fusion

Journal of ICT Research and Applications, 2014
Introducing motion sensors into smartphones contributed to a wide range of applications in human-phone interaction, gaming, and many others. However, built-in sensors that detect subtle motion changes (e.g.
Ahmed Al-Haiqi, Mahamod Ismail, Rosdiadee Nordin   +2 more
doaj   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

The Design of Flexible Rubber Tapping Tool with Settings the Depth and Thickness Control

IOP Conference Series: Materials Science and Engineering, 2019
Road map of land for agricultural commodities in West Aceh is prioritized for rubber plantations. This commodity is the main source of livelihood and employment for the commodity. Furthermore, it is very difficult for a novice tap to be able to control the depth, thickness, and slope of tapping angle.
H Susanto, S Ali, null Hanif
openaire   +1 more source

Use, adoption, and effectiveness of tippy-tap handwashing station in promoting hand hygiene practices in resource-limited settings: a systematic review [PDF]

BMC Public Health, 2019
Abstract Background Tippy-taps are locally made devices for washing hands with running water. They are simple and low-cost, enabling technology that provides adequate water sources, handwashing stations and motivation for people to prioritise handwashing.
Balwani Chingatichifwe Mbakaya, Fatch W. Kalembo, Maggie Zgambo   +2 more
openaire   +4 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Assessing the factors affecting maple syrup yield in the US and predicting production potential in Kentucky

Trees, Forests and People
Maple syrup is an important part of the economy in various regions of the United States. Studies on maple syrup production potential mostly use climatic factors as determinants and, therefore, fail to account for non-climatic factors.
Bobby Thapa, Thomas O. Ochuodho, John M. Lhotka, William Thomas, Zachary J. Hackworth, Jacob Muller, Thomas J. Brandeis, Edward Olale, Mo Zhou, Jingjing Liang   +9 more
doaj   +1 more source