Results 131 to 140 of about 709,020 (315)

Robust maximum weighted independent-set problems on interval graphs. [PDF]

open access: yes
We study the maximum weighted independent-set problem on interval graphs with uncertainty on the vertex weights. We use the absolute robustness criterion and the min-max regret criterion to evaluate solutions.
Leus, Roel, Talla Nobibon, Fabrice
core  

Thermal-aware SoC test scheduling with test set partitioning and interleaving

open access: yes, 2006
High temperature has become a major problem for system-on-chip testing. In order to reduce the test application time while keeping the temperatures of the cores under test within safe ranges, a thermal-aware test scheduling technique is required.
Peng, Zebo   +21 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Optimal Set-Membership Smoothing

open access: yesIEEE Transactions on Automatic Control
This article studies the Set-Membership Smoothing (SMSing) problem for non-stochastic Hidden Markov Models. By adopting the mathematical concept of uncertain variables, an optimal SMSing framework is established for the first time. This optimal framework reveals the principles of SMSing and the relationship between set-membership filtering and ...
Yudong Li   +3 more
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Empipe3D™ User’s Manual Version 4.0 -- PC

open access: yes, 1997
Empipe3D is a powerful and friendly software system for automated electromagnetic (EM) design optimization, driving the 3D field solvers Ansoft HFSS and HP HFSS.
Bandler, John W.   +3 more
core  

Level set methods for gradient-free optimization of metasurface arrays

open access: yesScientific Reports
Global optimization techniques are increasingly preferred over human-driven methods in the design of electromagnetic structures such as metasurfaces, and careful construction and parameterization of the physical structure is critical in ensuring ...
Alex Saad-Falcon   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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