Results 71 to 80 of about 12,357 (196)
Tackling High Dimensionality in QSP: Guiding Model Order Reduction With Index Analysis
ABSTRACT Quantitative systems pharmacology (QSP) models offer a useful platform to integrate drug pharmacology with knowledge about biological mechanisms across multiple scales and data sources into a unified quantitative framework. This makes them invaluable to address many relevant questions in drug research and development.
Johannes Tillil +2 more
wiley +1 more source
Mechanism Underlying Endothelium-Dependent Relaxation by 2-Methylthio-ADP in Monkey Cerebral Artery
We recently reported endothelium-dependent relaxation caused by nucleotides in the non-human primate cerebral artery. Here, we investigated the endothelium-dependent, nitric oxide- and prostanoid-independent relaxation induced by 2-methylthio-ADP ...
Ayman Geddawy +4 more
doaj +1 more source
The Glioma-associated Protein SETA Interacts with AIP1/Alix and ALG-2 and Modulates Apoptosis in Astrocytes [PDF]
Baihua Chen +4 more
openalex +1 more source
Abstract The genera of Miracinae, currently in something of a state of flux, are discussed with respect to their morphological and molecular attributes. Centistidea Rohwer, 1914 is treated provisionally as a valid genus, distinct from Mirax Haliday, 1833, based partly on propodeal morphology, though this is acknowledged to be an unstable character ...
Zhen Liu +2 more
wiley +1 more source
Comparison of Endothelium-Related Responses to Nucleotides of Dog and Monkey Cerebral Arteries
We compared mechanical responses to uridine-5′triphosphate (UTP) and 2-(methylthio)adenosine-5′diphosphate (2MeSADP) of cerebral arteries isolated from dogs and monkeys. In the dog, UTP induced endothelium-independent contraction, whereas 2MeSADP induced
Ayman Geddawy +4 more
doaj +1 more source
Abstract Four new species of Sycorax Haliday, 1839 are described: Sycorax alumna sp. nov., Sycorax catarina sp. nov., Sycorax paranaensis sp. nov., and Sycorax striga sp. nov., with the females of Sycorax striga sp. nov. bearing characteristics that suggest haematophagous behaviour.
Lucas Rossito +2 more
wiley +1 more source
To inform the development of effective prevention strategies for reducing pedestrian fatalities in an ageing society, a retrospective analysis was conducted on fatal pedestrian–vehicle collisions in Japan.
Masato Yamada +4 more
doaj +1 more source
Fetal Right Ventricular Diverticulum Detected by Prenatal Ultrasound Screening
Prenatal ultrasound screening has allowed for the detection of in utero cardiac abnormalities. Specifically, distinction is possible between ventricular diverticula and aneurysms, which is important because each condition has a different clinical outcome.
Daisuke Katsura +6 more
doaj +1 more source
Mills and society in early medieval northern Italy
Drawing on the extensive documentary record of northern Italy, available archaeological evidence, and comparative case studies from early medieval Europe, this study demonstrates that mill‐based landscapes in the Po and Friuli‐Venetian plains were shaped by society as a whole.
Marco Panato
wiley +1 more source
Yüzyıl Önce Türkiyede Eğitimin Sorunları
Osmanlı Devletinin son zamanlarında önemli görevlerde bulunmuş bir devlet adamı olan Avlonyalı Ferid Pasa. Mart 1898 ile Kasım 1902 tarihleri arasında Konya'da valilik yapmıştır.
Abdulhamit Kırmızı
doaj

