Results 151 to 160 of about 1,294,729 (367)
Advanced Science, EarlyView.Cai et al. report that tumor‐derived lactate induces NUPR1 expression via H3K18 lactylation, which can promote the pro‐tumor M2 macrophage polarization through ERK and JNK signaling pathways. Treatment with NUPR1 selective inhibitor sensitizes synergizes with anti‐PD‐1 therapy in murine preclinical models.
Jialiang Cai +12 more
wiley +1 more source
Evaluating the importance of environmental factors on the spatial distribution of livestock settlements in the Monte desert with a Monte Carlo based model: Settlement Dynamics in Drylands (SeDD) [PDF]
arXiv, 2015 In the Monte desert, increasing population density, changing land rights and infrastructure may encourage livestock activity, with unknown consequences on ecosystems. Factors that influence livestock settlement distribution may affect ecosystem degradation.
arxiv
Analysis of Farm Service Agency Direct Loan Loss Likelihoods and Loss Rates [PDF]
The USDA's Farm Service Agency (FSA) serves as the nation's lender of last resort by providing direct loans to farmers unable to obtain credit at reasonable rates and terms. Annual loan losses have been substantial, averaging $576 million for fiscal 1994-
Ahrendsen, Bruce L. +4 more
core +1 more source
Analysis of Problem Financing Settlement with Collateral of Land Certificate Without Binding Rights of Collaboration in the Perspective of Sharia Economic Law [PDF]
, 2023 Helmi Helmi, Denny Suwondo
openalex +1 more source
Digital currencies of central banks: memories of the fu ture
Интеллект. Инновации. ИнвестицииThe emergence of a new type of society in the wake of the information and digital revolution – Society 5.0. – is accompanied by social polarization, contributing to the occurrence and spread of technocratic metaphors with their humanitarian ...
E. I. Dyudikova
doaj +1 more source
Advanced Science, EarlyView.The study identifies a positive feed‐forward loop that intertwines DNA methylation regulator UHRF1 with Homeobox genes‐NKX2‐5/LHX1 via UMRs as a critical driver of ESCC. Pharmacological inhibition of UHRF1 and DNMT activity inhibits ESCC growth, which may represent a promising therapeutic approach to treat ESCC patients dependent on NKX2‐5/LHX1/UHRF1 ...
Xukun Li +13 more
wiley +1 more source
Mathematical Foundations for the Economy of Giving [PDF]
arXiv, 2014 This paper shows how we can build a model for transactions when goods are given away in the expectation of a later settlement. In settings where people keep track of their social accounts we are able to redefine concepts like account balance, yield curve and the law of diminishing returns.
arxiv
Advanced Science, EarlyView.In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao +19 more
wiley +1 more source
A Restatement of the Case for Fiscal Autonomy (or: The Barnett Formula - a formula for Rake's Progress) [PDF]
In this paper, we rebut the case that Ashcroft, Christie and Swales (2006) make in favour of the status quo fiscal settlement in Scotland that stems from the Scotland Act 1998.
P Hallwood, R.MacDonald
core