Results 201 to 210 of about 1,294,729 (367)

Lovo‐cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB‐206 study

American Journal of Hematology, Volume 98, Issue 1, Page 11-22, January 2023., 2023
Treatment process evolution. *The target TNC for BMH was ≥6 × 108/kg per patient. The Group B1 patient received lovo‐cel produced using both the original and refined manufacturing process, and the Group B2 patient received lovo‐cel produced using only the refined manufacturing process.
Julie Kanter, Alexis A. Thompson, Francis J. Pierciey Jr, Matthew Hsieh, Naoya Uchida, Philippe Leboulch, Manfred Schmidt, Melissa Bonner, Ruiting Guo, Alex Miller, Jean‐Antoine Ribeil, David Davidson, Mohammed Asmal, Mark C. Walters, John F. Tisdale   +14 more
wiley   +1 more source

m6A‐Mediated TMCO3 Promotes Hepatocellular Carcinoma Progression by Facilitating the Membrane Translocation and Activation of AKT

Advanced Science, EarlyView.
TMCO3 as a downstream target of ALKBH5 is found, which regulates its expression in an m6A‐dependent manner, and then a new phosphorylation site on TMCO3 is identified and determines the specific mechanism of TMCO3 with AKT. Moreover, the combined treatment of targeting the TMCO3 and inhibition of AKT in mice models with HCC achieves great results ...
Xinxin Li, Mengzhen Han, He Zhu, Yonglong Pan, Chen Su, Yachong Liu, Zhibin Liao, Bixiang Zhang, Xiaoping Chen   +8 more
wiley   +1 more source

A phase 1b study of venetoclax and azacitidine combination in patients with relapsed or refractory myelodysplastic syndromes

American Journal of Hematology, Volume 98, Issue 2, Page 272-281, February 2023., 2023
Abstract Patients with relapsed/refractory (R/R) higher‐risk myelodysplastic syndromes (MDS) have a dismal median overall survival (OS) after failing hypomethylating agent (HMA) treatment. There is no standard of care for patients after HMA therapy failure; hence, there is a critical need for effective therapeutic strategies.
Amer M. Zeidan, Uma Borate, Daniel A. Pollyea, Andrew M. Brunner, Fernando Roncolato, Jacqueline S. Garcia, Robin Filshie, Olatoyosi Odenike, Anne Marie Watson, Ravitharan Krishnadasan, Ashish Bajel, Kiran Naqvi, Jiuhong Zha, Wei‐Han Cheng, Ying Zhou, David Hoffman, Jason G. Harb, Jalaja Potluri, Guillermo Garcia‐Manero   +18 more
wiley   +1 more source

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

Advanced Science, EarlyView.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou, Xinyue Wang, Deyu Zhang, Hanxiao Cui, Xiaorong Tian, Wei Du, Zhenghui Yang, Dongling Wan, Zhiwei Qiu, Chao Liu, Zhicheng Yang, Lizhihong Zhang, Qiusheng Yang, Xuefeng Xu, Wenhao Li, Dong Wang, Haojie Huang, Wencheng Wu   +17 more
wiley   +1 more source

Is there a difference in student physical activity between a field school and a traditional classroom setting?

American Journal of Human Biology, Volume 34, Issue 12, December 2022., 2022
Abstract Objectives We compared the physical activity of nine students participating in an anthropological field school to their activity expenditures in traditional classrooms. We predicted that the students would exhibit higher physical activity during the field school due to the substantial physical requirements associated with the program compared ...
Michaela Emily Howells, Katherine L'Amour Woolard Mayfour, Taryn B. April, Richard L. Bender, James E. Loudon   +4 more
wiley   +1 more source

Ecofriendly Printing of Silver Nanowires with Cellulose Binder for Highly Robust Flexible Electronics

Advanced Electronic Materials, EarlyView.
This work reports ecofriendly silver nanowire based ink with cellulose as the binder for printed flexible electronics. After annealing, the cellulose binder provides excellent adhesion between nanowires and substrate, leading to robust electromechanical performance of the printed electronics without encapsulation.
Yuxuan Liu, Ping Ren, Li Yang, Brendan O'Connor, Jingyan Dong, Yong Zhu   +5 more
wiley   +1 more source

CURRENT TRENDS IN SETTLEMENTS AND PAYMENTS IN THE ISLAMIC FINANCE SYSTEM [PDF]

, 2023
S.Yu. Perseva
openalex   +1 more source

Financing Peace

, 2019
The international community is currently planning for a potential political settlement in Afghanistan. Negotiations may bring opportunities for significant reductions in violence. Government and development partners are considering how to support, consolidate, and sustain any reduction in ...
openaire   +1 more source

MANAJEMEN PENYELESAIAN PEMBIAYAAN BERMASALAH PADA LEMBAGA PERBANKAN SYARIAH

Li Falah: Jurnal Studi Ekonomi dan Bisnis Islam, 2016
Islamic financing products divided into three categories; (1) financing using the principle of trading is distinguished by a form of payment and delivery time of goods.
Muhamad Turmudi
doaj  

Polymeric Layered Films for TiO2‐Au/CuS Tandem Photothermal Catalytic H2 Production in Harsh Seawater and Waste Plastic Media

Advanced Energy Materials, EarlyView.
A spatially decoupled, polymeric passivated catalytic system is designed to facilitate pivotal photoprocesses such as photothermal, photogeneration‐charge separation, and redox at distinct locations. The proposed polymeric tandem photothermal catalytic (PTPC) film consists of TiO2/Au photocatalytic and CuS photothermal layers, spatially separated and ...
Minmin Gao, Tianxi Zhang, Serene Wen Ling Ng, Wanheng Lu, Guo Tian, Wei Li Ong, Sergey M. Kozlov, Ghim Wei Ho   +7 more
wiley   +1 more source