Results 31 to 40 of about 486,584 (353)

Eureka and beyond: mining's impact on African urbanisation [PDF]

, 2012
This collection brings separate literatures on mining and urbanisation together at a time when both artisanal and large-scale mining are expanding in many African economies. While much has been written about contestation over land and mineral rights, the
Anderson D.M., Appiah K.A., Bank L., Barnes T.J., Beall J., Bebbington A., Brands H.W., Bridge G., Bridge G., Bryceson D.F., Bryceson D.F., Bryceson D.F., Bryceson D.F., Bryceson D.F., Bryceson D.F., Buijtenhuis R., Carstens P., Cooper F., Coquery-Vidrovitch C., Danny MacKinnon, De Boeck F., De Boeck F., De Boeck F., Deborah Bryceson, Dore E., Duffy R., Emel J., Ferguson J., Freudenberg W.R., Freudenburg W.R., Freund W., Freund W.M., Gluckman M., Godfrey B.J., Grätz T., Harries P., Hilson G., Hilson G., Hilson G., Holliday J.S., Jeeves A., Johnston R.J., Jønsson J.B., Kirk J.F., Laverty J.R., Lawrie M., Le Billon P., Le Billon P., Luning S.W.J., Mabin A., Mabin A., Mkandawire T., Moodie T.D., Morris R.J., Morris R.J., O'Connor A., Parks R., Peters K., Potts D., Rajak D., Rakodi C., Richards P., Ross M., Saad E.N., Smith M.D., Storey K., Swanson M., Tonts M., Vennetier P., Verhoeve A., Walker R.A., Walsh A., Walsh A., Welsby D.A., Werthman K., Wilks I., Wilson L.J., Wolpe H.   +77 more
core   +5 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Unauthorized Immigrant Population: National and State Trends, 2010 [PDF]

, 2011
Analyzes trends in the estimated number of unauthorized immigrants overall, in the workforce, and of newborns with at least one unauthorized-immigrant parent.
D'Vera Cohn, Jeffrey S. Passel
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Connected peripheries – North Danube Thrace in the 4th-3rd centuries BC. Exploring settlement patterns in the environs of the ostentatious grave of Peretu [PDF]

Peuce, 2019
The following analysis emerged as an attempt to explain and contextualize a very rich grave, already historiographically notorious, with analogies equally famous, traditionally dated around the middle of the 4th c.
Maria-Magdalena ȘTEFAN, Dan ȘTEFAN
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Low population density settlement patterns on California's Northern Channel Islands

Frontiers in Environmental Archaeology
Chronological and archaeofaunal data indicate that settlement of the earliest, low-density populations on California's Northern Channel Islands was conditioned by variables other than those affecting later, high-density populations.
Christopher S. Jazwa, Tyler R. Molter, Christopher T. Morgan   +2 more
doaj   +1 more source

Paleogeography of Human Settlement at Iqaluktuuq, Victoria Island, Nunavut

Geosciences, 2022
Change in sea levels, be they isostatic or eustatic, impact humans and the paleogeography they inhabit. In this paper we examine paleogeography at Iqaluktuuq, a section of the Ekalluk River, Victoria Island, Nunavut, between Tahiryuaq (Ferguson Lake) and
Julie M. Ross, T. Max Friesen
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source