Results 41 to 50 of about 486,584 (353)

The BORDERSCAPE Project WebGIS: State Formation and Settlement Patterns near the Ancient Egyptian Southern Border

open access: yesJournal of Open Archaeology Data
The BORDERSCAPE Project WebGIS database and web app provide an overview of changes in the settlement pattern of the ancient Egyptian southern border during the long process of state formation and border-making.
Oren Siegel   +4 more
doaj   +1 more source

Evolving Cultural and Historical Landscapes of Northwestern Colchis during the Medieval Period: Physical Environment and Urban Decline Causes

open access: yesLand, 2022
In Late Antiquity and the Early Middle Ages, both coastal and sub-mountainous parts of Colchis underwent rapid urbanization. In the 12th century, the processes of decline began: Large settlements were replaced by small farmsteads with light wooden ...
Galina Trebeleva   +3 more
doaj   +1 more source

Northern Vanuatu as a Pacific Crossroads: The Archaeology of Discovery, Interaction, and the Emergence of the "Ethnographic Present" [PDF]

open access: yes, 2015
Northern Vanuatu is a significant crossroads region of the Southwest Pacific. This paper outlines current archaeological research being undertaken in the area, focusing on defining initial human settlement there some 3000 years ago and subsequent ...
Bedford, Stuart, Spriggs, Matthew
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Study of Settlement Pattern in Klaten District, Central Java Province

open access: yesForum Geografi, 2004
This study is aimed at studying spatial distribution patterns of settlement, inluding their variations and respective influencing facctors. The ultimated objetives to be ahieved are studying variation of dsitribution patterns of settlement, and the ...
Agus Dwi Martono
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Regional Demographic Trends and Settlement Patterns in Central Italy: Archaeological Sites and Radiocarbon Dates

open access: yesJournal of Open Archaeology Data, 2018
To our knowledge, the dataset described in this paper represents the largest existing repository of archaeological settlement (7,383 sites) and radiocarbon data (816 samples) for central Italy, spanning the period from the Late Mesolithic (ca.
Alessio Palmisano   +2 more
doaj   +1 more source

Political Settlements: Issues paper [PDF]

open access: yes, 2009
Why do similar sets of formal institutions often have such divergent outcomes? An analysis of political settlements goes some way to answering this question by bringing into focus the contending interests that exist within any state, which constrain and ...
Di John, Jonathan, Putzel, James
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

From the archaeology of settlement to the biography of landscapes: Polish archaeology and the contemporary prospects for research on the relationship between humans and the environment in the past

open access: yesPrzegląd Archeologiczny, 2019
The paper contains a review of theoretical and methodological approaches to the issue of archaeological research on the relationship between humans and their environment in the second half of the 20th and the beginning of the 21st century.
Zbigniew Kobyliński
doaj   +1 more source

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