Results 201 to 210 of about 8,548 (258)

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

Research on surrounding rock deformation characteristics and support optimization measures for tunnel TBM crossing through fault fracture zones. [PDF]

Sci Rep
Lan F, Du W, Li R, He C, He J, Yan J.
europepmc   +1 more source

Combining Radiation‐Treated Tumor Vaccines With Mn‐MOF Nanoadjuvants to Amplify Radiation Induced Anti‐Tumor Immune Responses

Advanced Science, EarlyView.
Radiotherapy‐treated tumor membranes are integrated with Mn‐MOF nanoadjuvants to generate Mn@RM, a lymph node‐draining nanovaccine that delivers radiotherapy‐remodeled antigenic components. Mn@RM enhances dendritic cell activation, amplifies T cell‐mediated antitumor immunity, and synergizes with radiotherapy and PD‐1 blockade for combination cancer ...
Yiyu Wang, Qiqi Qi, Dezhong Li, Jingshi Tang, Weifeng Wang, Zushun Xu, Qi Xu, Fangfang Du, Qianyuan He   +8 more
wiley   +1 more source

Flood risk prediction and modeling in Bauchi: Leveraging machine learning models and explainable AI for urban resilience. [PDF]

J Clim Chang Health
Kafi KM, Ponrahono Z, Ash'aari ZH, Barau AS.   +3 more
europepmc   +1 more source

The prediction of the progressive deformation mode based on active waveguide-generated acoustic emission. [PDF]

Sci Rep
Wu Z, Sun Y, Dong J, Liu B, Yu Y, Zhang L.   +5 more
europepmc   +1 more source

Improving the value of population health data for health policy and decision-making using machine learning algorithms in EQ-5D-5L index estimation. [PDF]

Sci Rep
Hölgyesi Á, Zrubka Z, Neshat M, Jáger V, Kincses Á, Kovács L, Gulácsi L, Mirjalili S, Péntek M.   +8 more
europepmc   +1 more source

Spatial prediction of animal plague risk in Qinghai Province, China using MaxEnt modeling: implications for targeted control. [PDF]

Front Vet Sci
Wang Y, Tang X, Yang Z, Ren Z, Yang J, Zhang A, Yuan Y, Zhou K, Jiang K, Duojie A, Wei Y, You P, Geng Y, Xu S, Zhang Q.   +14 more
europepmc   +1 more source

Pareto-optimized stacked ensemble machine learning framework for predicting bearing capacity of driven piles from static load test data. [PDF]

Sci Rep
Abdellatief M, ElNemr A, Altahrany A.
europepmc   +1 more source

SHAP-enhanced interpretive MGTWR-CNN-BILSTM-AM framework for predicting surface subsidence: a case study of Shanghai municipality. [PDF]

Sci Rep
Wen-Jiang L, Xue-Xiang Y, Ming-Fei Z, Li X, Guang-Hui Z, Lin-Lin W.   +5 more
europepmc   +1 more source

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Settlement predictions in the Anatolian Motorway, Turkey

Engineering Geology, 2002
The Anatolian Motorway through the Asarsuyu Valley passes across the landslides which have been extensively disturbed by past fault movements. The Asarsuyu Valley is the most important crossing of the motorway between Istanbul and Ankara route. Along the Asarsuyu Valley, about 7 km of the roadway is still under construction.
Dalgiç, Süleyman, Simşek, Orhan
openaire   +2 more sources